Evidence map›Paper›PMID 31810267›Full record

ArticleJournal of clinical medicine2019

The Right Time to Safely Re-Evaluate Empirical Antimicrobial Treatment of Hip or Knee Prosthetic Joint Infections.

Luc Deroche, Pascale Bémer, Anne-Sophie Valentin, Anne Jolivet-Gougeon, Didier Tandé, Geneviève Héry-Arnaud, Carole Lemarié, Marie Kempf, Laurent Bret, Christophe Burucoa and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Luc DerocheBacteriology-Hospital Hygiene Department, University Hospital of Poitiers, Poitiers Universiy, F-86000 Poitiers, France.ORCID 0000-0002-9985-7375
Pascale BémerBacteriology-Hospital Hygiene Department, University Hospital of Nantes, Nantes University, F-44000 Nantes, France.
Anne-Sophie ValentinBacteriology-Hospital Hygiene Department, University Hospital of Tours, Tours University, F-37000 Tours, France.
Anne Jolivet-GougeonUniv Rennes, INSERM, University Hospital of Rennes, NUMECAN Institute (Nutrition Metabolisms and Cancer), F-35000 Rennes, France.
Didier TandéBacteriology-Hospital Hygiene Department, University Hospital of Brest, Brest University, F-29000 Brest, France.
Geneviève Héry-ArnaudBacteriology-Hospital Hygiene Department, University Hospital of Brest, Brest University, F-29000 Brest, France.
Carole LemariéBacteriology-Hospital Hygiene Department, University Hospital of Angers, Angers University, F-49000 Angers, France.
Marie KempfBacteriology-Hospital Hygiene Department, University Hospital of Angers, Angers University, F-49000 Angers, France.
Laurent BretBacteriology-Hospital Hygiene Department, Hospital of Orléans, F-45000 Orléans, France.
Christophe BurucoaBacteriology-Hospital Hygiene Department, University Hospital of Poitiers, Poitiers Universiy, F-86000 Poitiers, France.
Stéphane CorvecBacteriology-Hospital Hygiene Department, University Hospital of Nantes, Nantes University, F-44000 Nantes, France.ORCID 0000-0003-3176-8111
Chloé PlouzeauBacteriology-Hospital Hygiene Department, University Hospital of Poitiers, Poitiers Universiy, F-86000 Poitiers, France.
Université de Poitiers · FRCentre Hospitalier Régional Universitaire de Brest · FRNantes Université · FRUniversité d'Angers · FRCentre hospitalier universitaire d'Orléans · FRInserm · FRUniversité de Tours · FR

Funding

French Ministry of Health (Programme Hospitalier de Recherche Clinique Interrégionale) API/N/041
6 · The paper itself

Abstract

Currently, no guideline provides recommendations on the duration of empirical antimicrobial treatment (EAT) in prosthetic joint infection (PJI). The aim of our study was to describe the time to growth of bacteria involved in PJI, rendering possible decreased duration of EAT. Based on a French multicentre prospective cohort study, culture data from patients with confirmed hip or knee PJI were analysed. For each patient, five samples were processed. Time to positivity was defined as the first positive medium in at least one sample for virulent pathogens and as the first positive medium in at least two samples for commensals. Definitive diagnosis of polymicrobial infections was considered the day the last bacteria were identified. Among the 183 PJIs, including 28 polymicrobial infections, microbiological diagnosis was carried out between Day 1 (D1) and D5 for 96.7% of cases. There was no difference in the average time to positivity between acute and chronic PJI (

Indexed as

bacterial growth timeempirical antimicrobial treatmentpostoperative antibioticsprosthetic joint infectiontime to positivity

Identifiers

PMID31810267
PMCPMC6947470
OpenAlexW2993520627

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.