Evidence map›Paper›PMID 31810248›Full record

ArticlePharmaceuticals (Basel, Switzerland)2019

In Vitro Characterization and Stability Profiles of Antibody-Fluorophore Conjugates Derived from Interchain Cysteine Cross-Linking or Lysine Bioconjugation.

Camille Martin, Guillaume Brachet, Cyril Colas, Emilie Allard-Vannier, Claire Kizlik-Masson, Clara Esnault, Renaud Respaud, Caroline Denevault-Sabourin, Igor Chourpa, Valérie Gouilleux-Gruart and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Camille MartinGICC EA7501, Equipe IMT, Université de Tours, UFR des Sciences Pharmaceutiques, 31 Avenue Monge, 37200 Tours, France.
Guillaume BrachetLaboratoire d'immunologie, CHRU Tours, 10 Bd Tonnelé, 37000 Tours, France.
Cyril ColasICOA UMR 7311 CNRS, Université d'Orléans, Pôle de Chimie, Rue de Chartres, BP 6759, 45067 Orléans CEDEX 2, France.
Emilie Allard-VannierNMNS EA 6295, 31 Avenue Monge, 37200 Tours, France.
Claire Kizlik-MassonGICC EA7501, Equipe FRAME, Université de Tours, 10 Bd Tonnelé, 37000 Tours, France.
Clara EsnaultGICC EA7501, Equipe IMT, Université de Tours, UFR des Sciences Pharmaceutiques, 31 Avenue Monge, 37200 Tours, France.
Renaud RespaudINSERM U1100, Université de Tours, 10 Bd Tonnelé, 37000 Tours, France.
Caroline Denevault-SabourinGICC EA7501, Equipe IMT, Université de Tours, UFR des Sciences Pharmaceutiques, 31 Avenue Monge, 37200 Tours, France.
Igor ChourpaNMNS EA 6295, 31 Avenue Monge, 37200 Tours, France.
Valérie Gouilleux-GruartLaboratoire d'immunologie, CHRU Tours, 10 Bd Tonnelé, 37000 Tours, France.
Marie-Claude Viaud-MassuardGICC EA7501, Equipe IMT, Université de Tours, UFR des Sciences Pharmaceutiques, 31 Avenue Monge, 37200 Tours, France.
Nicolas JoubertGICC EA7501, Equipe IMT, Université de Tours, UFR des Sciences Pharmaceutiques, 31 Avenue Monge, 37200 Tours, France.
Université de Tours · FRUniversité d'Orléans · FR

Funding

Agence Nationale de la Recherche ANR-10-LABX-53-01Agence Nationale de la Recherche ANR-11-LABX-0029Région Centre Val de Loire -
6 · The paper itself

Abstract

Fluorescent labelling of monoclonal antibodies (mAbs) is classically performed by chemical bioconjugation methods. The most frequent labelling technique to generate antibody-fluorophore conjugates (AFCs) involves the bioconjugation onto the mAb lysines of a dye bearing an

Indexed as

antibody–fluorophore conjugatebioconjugationfluorescencelabelling

Identifiers

PMID31810248
PMCPMC6958397
OpenAlexW2991101948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.