Trial reportNutrients2019
A Randomised Trial to Optimise Gestational Weight Gain and Improve Maternal and Infant Health Outcomes through Antenatal Dietary, Lifestyle and Exercise Advice: The OPTIMISE Randomised Trial.
Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Effects of lifestyle interventions in pregnancy on gestational diabetes: individual participant data and network meta-analysis.BMJ (Clinical research ed.) · 2026Pooled it
- Energy intake and physical activity over the course of pregnancy and gestational weight gain: a systematic review and dose-response meta-analysis of data from randomized controlled lifestyle intervention trials.Nutrition journal · 2025Pooled it
- Is Maternal Carbohydrate Intake Having an Impact on Newborn Birth Weight? A Systematic Review.Nutrients · 2023Pooled it
- Physical exercise interventions for perinatal depression symptoms in women: A systematic review and meta-analysis.Frontiers in psychology · 2022Pooled it
- Effects of Maternal Exercise During Pregnancy on Perinatal Growth and Childhood Obesity Outcomes: A Meta-analysis and Meta-regression.Sports medicine (Auckland, N.Z.) · 2021Pooled it
- Fetal Growth and Adiposity of Infants Born Large for Gestational Age in Three Harmonized Randomized Trials.American journal of perinatology · 2024Trial
- Handling misclassified stratification variables in the analysis of randomised trials with continuous outcomes.Statistics in medicine · 2023Trial
- Trial
- Trial
- Trial
- Effects of the First 1000 Days Program, a systems-change intervention, on obesity risk factors during pregnancy.BMC pregnancy and childbirth · 2021Trial
- Gestational Weight Gain-Re-Examining the Current Paradigm.Nutrients · 2020Trial
- Cardiometabolic Health in Pregnancy: Prevention, Management, and Long-Term Implications.JACC. Advances · 2026Review
- Effects of Combined Diet and Physical Activity on Gestational Weight Gain in Low-Risk Pregnant Women Based on the TIDieR Checklist: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- A CFIR-Guided Qualitative Process Evaluation of a Health Insurance-Based Lifestyle Counseling Intervention During Pregnancy in Germany.International journal of women's health · 2026Article
- Mental health and body mass index in early pregnancy: a secondary analysis of three randomised controlled trials.BMC pregnancy and childbirth · 2025Article
- Associations among parental mental health, lifestyle factors and infant mortality in rural and urban mothers.Frontiers in public health · 2025Article
- Exercise During Pregnancy—Effects on Birth Weight and on the Risks of Gestational Diabetes and Preterm Delivery.Deutsches Arzteblatt international · 2022Review
- Effectiveness of a nurse practitioner-led cardiovascular prevention clinic at reduction of metabolic syndrome following maternal complications of pregnancy: a preliminary analysis.Diabetology & metabolic syndrome · 2022Article
- Physical activity during pregnancy: a systematic review for the assessment of current evidence with future recommendations.BMC sports science, medicine & rehabilitation · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
There are well-recognised associations between excessive gestational weight gain (GWG) and adverse pregnancy outcomes, including an increased risk of pre-eclampsia, gestational diabetes and caesarean birth. The aim of the OPTIMISE randomised trial was to evaluate the effect of dietary and exercise advice among pregnant women of normal body mass index (BMI), on pregnancy and birth outcomes. The trial was conducted in Adelaide, South Australia. Pregnant women with a body mass index in the healthy weight range (18.5-24.9 kg/m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.