Evidence map›Paper›PMID 31810155›Full record

ArticleNutrients2019

Vitamin D Concentration during Early Pregnancy and Adverse Outcomes among HIV-Negative Women in Dar-es-Salaam, Tanzania: A Case-Control Study.

Aneth V Kalinjuma, Anne Marie Darling, Christopher R Sudfeld, Ferdinand Mugusi, Julie Wright, Ajibola I Abioye, Said Aboud, Chloe McDonald, Ellen Hertzmark, Kevin C Kain and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aneth V KalinjumaIntervention and Clinic Trials Department, Ifakara Health Institute, P.O. Box 53, Ifakara, Morogoro, Tanzania.ORCID 0000-0001-5862-9264
Anne Marie DarlingDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Christopher R SudfeldDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Ferdinand MugusiDepartments of Internal Medicine; and Microbiology and Immunology, School of Medicine, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, Dar-es-Salaam, Tanzania.
Julie WrightDepartment of Medicine, Tropical Disease Unit, University Health Network-Toronto General Hospital, University of Toronto, Toronto, ON M5G 1L7, Canada.
Ajibola I AbioyeDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Said AboudDepartments of Internal Medicine; and Microbiology and Immunology, School of Medicine, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, Dar-es-Salaam, Tanzania.
Chloe McDonaldDepartment of Medicine, Tropical Disease Unit, University Health Network-Toronto General Hospital, University of Toronto, Toronto, ON M5G 1L7, Canada.
Ellen HertzmarkDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Kevin C KainDepartment of Medicine, Tropical Disease Unit, University Health Network-Toronto General Hospital, University of Toronto, Toronto, ON M5G 1L7, Canada.
Wafaie W FawziDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

Funding

Tanzania Infectious Disease Research Training ProgramD43TW007886 · FIC · HARVARD SCHOOL OF PUBLIC HEALTH · PI FAWZI, WAFAIE W · 2007 to 2018
$1.9M
FIC NIH HHS D43 TW007886Global Infectious Diseases (GID) training program sponsored by the U.S. National Institute of Health (NIH) Fogarty International Center D43 TW 007886
6 · The paper itself

Abstract

We examined the associations of plasma vitamin D concentration and adverse pregnancy outcomes among HIV-negative women in Dar-es-Salaam, Tanzania. We used an unmatched case-control study design, with 25-hydroxyvitamin D [25(OH)D] concentration assessed in the first trimester. Cases were individuals with adverse pregnancy outcomes, including stillbirth, premature birth, or small for gestational age births (SGA). Unconditional logistic regression and weighted logistic regression models were used to describe the associations of 25(OH)D concentration with the composite of adverse pregnancy outcome and individual adverse pregnancy outcomes, respectively. We included 310 cases and 321 controls. In controls, 5(2%) were vitamin D deficient (25(OH)D < 20 ng/mL), and 17(5%) had insufficient 25(OH)D concentration (20.0-29.9 ng/mL). Women with 25(OH)D < 20 ng/mL had 1.82 times the odds of occurrence of the composite adverse pregnancy outcome (OR = 1.82, 95% CI: 0.56-5.93;

Indexed as

AdultCase-Control StudiesFemaleHumansInfant, NewbornInfant, Small for Gestational AgeNutritional StatusPregnancyPregnancy ComplicationsPregnancy OutcomePregnancy Trimester, FirstPremature BirthStillbirthTanzaniaVitamin DVitamin D Deficiency25-hydroxyvitamin DVitamin Dfirst trimesternon-linearpregnant womenprematuresmall for gestational agestillbirthvitamin D concentration

Identifiers

PMID31810155
PMCPMC6949980

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.