ArticleNeuroImage2020
Higher resting-state BNST-CeA connectivity is associated with greater corrugator supercilii reactivity to negatively valenced images.
Article in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Bed nucleus of the stria terminalis connectivity during food cue and taste processing under stress.Nature communications · 2026Article
- GABAergic neurons in central amygdala contribute to orchestrating anxiety-like behaviors and breathing patterns.Nature communications · 2025Article
- Understanding the heterogeneity of anxiety using a translational neuroscience approach.Cognitive, affective & behavioral neuroscience · 2024Review
- Alterations in BNST Intrinsic Functional Connectivity in Early Abstinence from Alcohol Use Disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2023Article
- White matter microstructure predicts individual differences in infant fear (But not anger and sadness).Developmental science · 2023Article
- Subiculum-BNST structural connectivity in humans and macaques.NeuroImage · 2022Article
- Individual variation in white matter microstructure is related to better recovery from negative stimuli.Emotion (Washington, D.C.) · 2022Article
- BNST and amygdala connectivity are altered during threat anticipation in schizophrenia.Behavioural brain research · 2021Article
- Extended-amygdala intrinsic functional connectivity networks: A population study.Human brain mapping · 2021Article
- Differences in Emotion Expression, Suppression, and Cardiovascular Consequences Between Black and White Americans in the Midlife in the United States (MIDUS) Study.Psychosomatic medicineArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
The bed nucleus of the stria terminalis (BNST) and central nucleus of the amygdala (CeA) are hypothesized to be the output nodes of the extended amygdala threat response, integrating multiple signals to coordinate the threat response via outputs to the hypothalamus and brainstem. The BNST and CeA are structurally and functionally connected, suggesting interactions between these regions may regulate how the response to provocation unfolds. However, the relationship between human BNST-CeA connectivity and the behavioral response to affective stimuli is little understood. To investigate whether individual differences in BNST-CeA connectivity are related to the affective response to negatively valenced stimuli, we tested relations between resting-state BNST-CeA connectivity and both facial electromyographic (EMG) activity of the corrugator supercilii muscle and eyeblink startle magnitude during affective image presentation within the Refresher sample of the Midlife in the United States (MIDUS) study. We found that higher right BNST-CeA connectivity was associated with greater corrugator activity to negative, but not positive, images. There was a trend-level association between right BNST-CeA connectivity and trait negative affect. Eyeblink startle magnitude was not significantly related to BNST-CeA connectivity. These results suggest that functional interactions between BNST and CeA contribute to the behavioral response to negative emotional events.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.