Evidence map›Paper›PMID 31809791›Full record

ArticleJournal of cardiac failure2020

Impact of Socioeconomic Factors on Patient Desire for Early LVAD Therapy Prior to Inotrope Dependence.

Inna Tchoukina, Keyur B Shah, Jennifer T Thibodeau, Jerry D Estep, Anuradha Lala, David E Lanfear, Nisha A Gilotra, Salpy V Pamboukian, Douglas A Horstmanshof, Dennis M Mcnamara and 13 more

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiac failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Review
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 16 institutions in 1 country.

Inna TchoukinaVirginia Commonwealth University, Richmond, Virginia. Electronic address: inna.tchoukina@vcuhealth.org.
Keyur B ShahVirginia Commonwealth University, Richmond, Virginia.
Jennifer T ThibodeauUniversity of Texas Southwestern Medical Center, Dallas, Texas.
Jerry D EstepCleveland Clinic, Cleveland, Ohio.
Anuradha LalaMount Sinai Icahn School of Medicine, New York, New York.
David E LanfearHenry Ford Hospital, Detroit, Michigan.
Nisha A GilotraJohns Hopkins University School of Medicine, Baltimore, Maryland.
Salpy V PamboukianUniversity of Alabama at Birmingham, Birmingham, Alabama.
Douglas A HorstmanshofINTEGRIS Baptist Medical Center, Oklahoma City, Oklahoma.
Dennis M McnamaraUniversity of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Donald C HaasAbington-Jefferson Health, Abington, Pennsylvania.
Ulrich P JordeMontefiore Medical Center, Bronx, New York.
Rhondalyn C McleanUniversity of Pennsylvania, Philadelphia, Pennsylvania.
Thomas M CascinoUniversity of Michigan, Ann Arbor, Michigan.
Shokoufeh KhalatbariUniversity of Michigan, Ann Arbor, Michigan.
Blair RichardsUniversity of Michigan, Ann Arbor, Michigan.
Matheos YosefUniversity of Michigan, Ann Arbor, Michigan.
Cathie SpinoUniversity of Michigan, Ann Arbor, Michigan.
J Timothy BaldwinNational Heart, Lung, and Blood Institute, Bethesda, Maryland.
Douglas L MannWashington University, St. Louis, Missouri.
Keith D AaronsonUniversity of Michigan, Ann Arbor, Michigan.
Garrick C StewartBrigham and Women's Hospital, Boston, Massachusetts.
REVIVAL Investigators
University of Michigan–Ann Arbor · USVirginia Commonwealth University · USAbington Memorial Hospital · USBrigham and Women's Hospital · USCleveland Clinic · USHenry Ford Hospital · USIcahn School of Medicine at Mount Sinai · USINTEGRIS Baptist Medical Center · USJohns Hopkins Medicine · USMontefiore Medical Center · USNational Heart Lung and Blood Institute · USThe University of Texas Southwestern Medical Center · USUniversity of Alabama at Birmingham · USUniversity of Pennsylvania · USUniversity of Pittsburgh Medical Center · USWashington University in St. Louis · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Impact of Race and Genetic Factors on Beta-blocker Effectiveness in Heart FailureR01HL103871 · NHLBI · HENRY FORD HEALTH SYSTEM · PI LANFEAR, DAVID E · 2011 to 2015
$3.5M
Plasma Metabolomics and Myocardial Energetics in Heart FailureR01HL132154 · NHLBI · HENRY FORD HEALTH SYSTEM · PI LANFEAR, DAVID E, SABBAH, HANI N · 2017 to 2020
$3.1M
NCATS NIH HHS UL1 TR002240NHLBI NIH HHS HHSN268201100026CNHLBI NIH HHS R01 HL103871NHLBI NIH HHS R01 HL132154
6 · The paper itself

Abstract

backgroundWorsening heart failure (HF) and health-related quality of life (HRQOL) have been shown to impact the decision to proceed with left ventricular assist device (LVAD) implantation, but little is known about how socioeconomic factors influence expressed patient preference for LVAD. METHODS AND

resultsAmbulatory patients with advanced systolic HF (n=353) reviewed written information about LVAD therapy and completed a brief survey to indicate whether they would want an LVAD to treat their current level of HF. Ordinal logistic regression analyses identified clinical and demographic predictors of LVAD preference. Higher New York Heart Association (NYHA) class, worse HRQOL measured by Kansas City Cardiomyopathy Questionnaire, lower education level, and lower income were significant univariable predictors of patients wanting an LVAD. In the multivariable model, higher NYHA class (OR [odds ratio]: 1.43, CI [confidence interval]: 1.08-1.90, P = .013) and lower income level (OR: 2.10, CI: 1.18 - 3.76, P = .012 for <$40,000 vs >$80,000) remained significantly associated with wanting an LVAD.

conclusionAmong ambulatory patients with advanced systolic HF, treatment preference for LVAD was influenced by level of income independent of HF severity. Understanding the impact of socioeconomic factors on willingness to consider LVAD therapy may help tailor counseling towards individual needs.

Indexed as

Heart-Assist DevicesHeart FailureHumansProspective StudiesQuality of LifeSocioeconomic FactorsTreatment Outcomedecision-makingheart failuresocioeconomic statusVentricular assist device

Identifiers

PMID31809791
PMCPMC7141955
OpenAlexW2992683061

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.