Evidence map›Paper›PMID 31809423›Full record

ArticleObstetrics and gynecology2020

Expectant Management of Hypertensive Disorders of Pregnancy and Future Cardiovascular Morbidity.

Joshua I Rosenbloom, Adam K Lewkowitz, Kathryn J Lindley, D Michael Nelson, George A Macones, Alison G Cahill, Margaret A Olsen, Molly J Stout

Open access · bronzeAbstract read
In one paragraph

Article in Obstetrics and gynecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Hypertensive Disorders of Pregnancy.Cardiology clinics · 2021
    Review
  7. Observational
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Joshua I RosenbloomDepartment of Obstetrics and Gynecology, the Division of Cardiology, Department of Internal Medicine, and the Center for Administrative Data Research, Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri.
Adam K Lewkowitz
Kathryn J Lindley
D Michael Nelson
George A Macones
Alison G Cahill
Margaret A Olsen
Molly J Stout
Twitter (United States) · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
WASHINGTON UNIVERSITY COMPARATIVE EFFECTIVENESS ADMINISTRATIVE DATA REPOSITORYR24HS019455 · AHRQ · WASHINGTON UNIVERSITY · PI FRASER, VICTORIA J. · 2010 to 2010
$969k
AHRQ HHS R24 HS019455NCATS NIH HHS UL1 TR002345
6 · The paper itself

Abstract

objectiveTo test the hypothesis that a longer length of time between diagnosis of hypertensive disorders of pregnancy and delivery is associated with increased risk of cardiovascular morbidity in the years after delivery.

methodsThis is a retrospective cohort study based in the New York State Inpatient Database. The first delivery for all patients from 2005 to 2014 who delivered preterm with an International Classification of Diseases, 9th Revision, Clinical Modification code for hypertensive disorders of pregnancy (excluding isolated chronic hypertension) was included. The duration between diagnosis and delivery was divided into 7 days or less or more than 7 days. The primary outcome was admission for a composite of cardiovascular disease, stroke, or death after the index delivery through December 31, 2014.

resultsThere were 22,594 patients with a median follow-up period of 5.2 years: 19,750 (87.4%) were delivered within 7 days of diagnosis and 2,844 (12.6%) were delivered more than 7 days from diagnosis. The primary outcome occurred in 216 (1.1%) patients in the 0-7 days group (21 events/10,000 person-years) and 67 (2.4%) patients in the more than 7 days group (46 events/10,000 person-years), adjusted hazard ratio 1.45 (95% CI 1.09 to 1.93). The findings were robust in a number of sensitivity analyses.

conclusionsProlonged expectant management of preterm hypertensive disorders of pregnancy is associated with an increased risk of maternal cardiac disease in the ensuing years.

Indexed as

Delivery, ObstetricWatchful WaitingAdultCardiovascular DiseasesDatabases, FactualFemaleGestational AgeHumansHypertension, Pregnancy-InducedInfant, NewbornLogistic ModelsNew YorkPregnancyPregnancy Complications, CardiovascularPregnancy OutcomePregnancy Trimester, Third

Identifiers

PMID31809423
PMCPMC6923587
OpenAlexW2994441207

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.