Evidence map›Paper›PMID 31809218›Full record

ReviewExpert opinion on drug safety2020

Safety implications of combined antiretroviral and anti-tuberculosis drugs.

Maddalena Cerrone, Margherita Bracchi, Sean Wasserman, Anton Pozniak, Graeme Meintjes, Karen Cohen, Robert J Wilkinson

Open access · greenAbstract readReview
In one paragraph

Review in Expert opinion on drug safety, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Clinical Outcomes in Children With Human Immunodeficiency Virus Treated for Nonsevere Tuberculosis in the SHINE Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Patient Determinants and Effects on Adherence of Adverse Drug Reactions to Tuberculosis Treatment: A Prospective Cohort Analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  10. Article
  11. Article
  12. An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Review
  14. Incidence and Predictors of Severe Adverse Drug Reactions among Patients on Antiretroviral Drugs in Harari Regional State, Eastern Ethiopia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Article
  15. Review
  16. Review
  17. Antibodies as clinical tools for tuberculosis.Frontiers in immunology · 2023
    Review
  18. Review
  19. Clinical standards for the dosing and management of TB drugs.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Maddalena CerroneDepartment of Medicine, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-6900-6086
Margherita BracchiDepartment of HIV, Chelsea and Westminster Hospital NHS Trust, London, UK.
Sean WassermanWellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Observatory, South Africa.ORCID https://orcid.org/0000-0002-3508-6719
Anton PozniakDepartment of HIV, Chelsea and Westminster Hospital NHS Trust, London, UK.
Graeme MeintjesWellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Observatory, South Africa.
Karen CohenDivision of Clinical Pharmacology, Department of Medicine, University of Cape Town, Rondebosch, South Africa.ORCID https://orcid.org/0000-0002-1892-4207
Robert J WilkinsonDepartment of Medicine, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-2753-1800
University of Cape Town · ZAChelsea and Westminster Hospital · GBLondon School of Hygiene & Tropical Medicine · GB

Funding

Inflammatory determinants of disease severity and treatment outcome in TB patientsU01AI115940 · NIAID · UNIVERSITY OF CAPE TOWN · PI SHER, ALAN, WILKINSON, ROBERT JOHN · 2015 to 2019
$1.1M
NIAID NIH HHS U01 AI115940Wellcome Trust 104803Wellcome Trust 203135
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-HIV AgentsAntitubercular AgentsDrug InteractionsHIV InfectionsHumansLatent TuberculosisTuberculosisAnti-HIV AgentsAntitubercular Agentsantiretroviraldrug interactionsHIVsafetytoxicityTuberculosis

Identifiers

PMID31809218
PMCPMC6938542
OpenAlexW2994448962

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.