Evidence map›Paper›PMID 31808983›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Self-Amplified Photodynamic Therapy through the

Zhiyong Liu, Tianye Cao, Yudong Xue, Mengting Li, Mengsi Wu, Jonathan W Engle, Qianjun He, Weibo Cai, Minbo Lan, Weian Zhang

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 92 citations in OpenAlex.

  1. Review
  2. Hollow MnOInternational journal of nanomedicine · 2026
    Article
  3. Review
  4. Phototherapy in cancer treatment: strategies and challenges.Signal transduction and targeted therapy · 2025
    Review
  5. Engineered cyanobacteria-FeMaterials today. Bio · 2024
    Article
  6. Fluorescent small molecule donors.Chemical Society reviews · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Advances in photosensitizer-related design for photodynamic therapy.Asian journal of pharmaceutical sciences · 2021
    Review
  20. Switching Reactive Oxygen Species into Reactive Nitrogen Species by Photocleaved OAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Zhiyong LiuShanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
Tianye CaoDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Yudong XueShanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
Mengting LiDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Mengsi WuShanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
Jonathan W EngleDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Qianjun HeGuangdong Provincial Key Laboratory of Biomedical Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for, Medical Ultrasound, School of Biomedical Engineering, Health Science Center, Shenzhen University, No. 1066 Xueyuan Road, Nanshan District, Shenzhen, 518060, Guangdong, China.
Weibo CaiDepartments of Radiology and Medical Physics, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Minbo LanShanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.
Weian ZhangShanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.ORCID 0000-0002-1717-597X
East China University of Science and Technology · CNUniversity of Wisconsin–Madison · USShenzhen University Health Science Center · CN

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
NCI NIH HHS P30 CA014520
6 · The paper itself

Abstract

Nanocarriers are employed to deliver photosensitizers for photodynamic therapy (PDT) through the enhanced penetration and retention effect, but disadvantages including the premature leakage and non-selective release of photosensitizers still exist. Herein, we report a

Indexed as

AnimalsCell Line, TumorCell SurvivalChlorophyllInfrared RaysMelanoma, ExperimentalMiceMicroscopy, ConfocalNanoparticlesParticle SizePhotochemotherapyPhotosensitizing AgentsPolyethylene GlycolsPolymersPorphyrinsPositron-Emission TomographyChlorophyllPhotosensitizing AgentsPOEGMAPolyethylene GlycolsPolymersPorphyrinspyropheophorbide aSinglet Oxygenblock copolymerdrug deliveryphotodynamic therapyreactive oxygen speciesself-amplification

Identifiers

PMID31808983
PMCPMC7028480
OpenAlexW2993278204

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.