Evidence map›Paper›PMID 31808676›Full record

ArticleACS infectious diseases2020

Setting Our Sights on Infectious Diseases.

Manu De Rycker, David Horn, Bree Aldridge, Richard K Amewu, Clifton E Barry, Frederick S Buckner, Sarah Cook, Michael A J Ferguson, Nathalie Gobeau, Jennifer Herrmann and 27 more

Abstract read
In one paragraph

Article in ACS infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Science translational medicine · 2024
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. ACS infectious diseases · 2021
    Review
  10. Article
  11. Physicochemical properties andRSC medicinal chemistry · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Manu De RyckerWellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery , University of Dundee , Dundee DD1 5EH , United Kingdom.ORCID 0000-0002-3171-3519
David HornWellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery , University of Dundee , Dundee DD1 5EH , United Kingdom.
Bree AldridgeTufts University School of Medicine , 136 Harrison Avenue , Boston , Massachusetts 02111 , United States.
Richard K AmewuDepartment of Chemistry , University of Ghana , P.O. Box LG56, Legon, Accra , Ghana.
Clifton E BarryNational Institute of Allergy and Infectious Diseases , National Institutes of Health , 9000 Rockville Pike , Bethesda , Maryland 20892 , United States.
Frederick S BucknerCenter for Emerging and Re-emerging Infectious Diseases (CERID) , University of Washington , MS 358061, 750 Republican Street , Rm E-606, Seattle , Washington 98109-4766 , United States.ORCID 0000-0001-7796-6477
Sarah CookSchool of Humanities , University of Glasgow , 1 University Gardens , Glasgow G12 8QQ , United Kingdom.
Michael A J FergusonWellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery , University of Dundee , Dundee DD1 5EH , United Kingdom.
Nathalie GobeauMedicines for Malaria Venture (MMV) , PO Box 1826, 20 Route de Pré-Bois , 1215 Geneva 15, Switzerland.
Jennifer HerrmannHelmholtz Institute for Pharmaceutical Research Saarland, Department Microbial Natural Products , Saarland University , Campus E8.1, 66123 Saarbrücken , Germany.
Paul HerrlingIndependent Consultant, Switzerland.
William HopeInstitute of Translational Medicine , University of Liverpool , Liverpool L69 3BX , United Kingdom.
Jennifer KeiserDepartment of Medical Parasitology and Infection Biology , Swiss Tropical and Public Health Institute , Socinstrasse 57 , CH-4051 Basel , Switzerland.ORCID 0000-0003-0290-3521
Maria Jose Lafuente-MonasterioTres Cantos Medicines Development Campus, Diseases of the Developing World (DDW) , GlaxoSmithKline , Tres Cantos , Spain.
Paul D LeesonPaul Leeson Consulting Ltd. , United Kingdom.ORCID 0000-0003-0212-3437
Didier LeroyMedicines for Malaria Venture (MMV) , PO Box 1826, 20 Route de Pré-Bois , 1215 Geneva 15, Switzerland.
Ujjini H ManjunathaNovartis Institute for Tropical Diseases (NITD) , Novartis Institutes for BioMedical Research (NIBR) , 5300 Chiron Way , Emeryville , California 94608 , United States.ORCID 0000-0002-7461-9303
James McCarthyQIMR Berghofer Medical Research Institute , 300 Herston Road , Hertson , Queensland 4006 , Australia.
Timothy J MilesTres Cantos Medicines Development Campus, Diseases of the Developing World (DDW) , GlaxoSmithKline , Tres Cantos , Spain.ORCID 0000-0001-7407-7404
Valerie MizrahiSAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Institute of Infectious Disease and Molecular Medicine and Wellcome Centre for Infectious Disease Research in Africa , University of Cape Town , Observatory, Cape Town 7925 , South Africa.ORCID 0000-0003-4824-9115
Olena MoshynetsBiofilm Study Group , Institute of Molecular Biology and Genetics of National Academy of Sciences of Ukraine , 150 Zabolotnoho Street , Kiev 03143 , Ukraine.
Jacquin NilesSchool of Engineering , Massachusetts Institute of Technology , Building 1-206, 77 Massachusetts Avenue , Cambridge , Massachusetts 02139-4307 , United States.
John P OveringtonMedicines Discovery Catapult , Alderley Park, Alderley Edge, Cheshire SK10 4TG , United Kingdom.ORCID 0000-0002-5859-1064
John PottageViiV Healthcare , 980 Great West Road , Brentford , Middlesex TW8 9GS , United Kingdom.
Srinivasa P S RaoNovartis Institute for Tropical Diseases (NITD) , Novartis Institutes for BioMedical Research (NIBR) , 5300 Chiron Way , Emeryville , California 94608 , United States.
Kevin D ReadWellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery , University of Dundee , Dundee DD1 5EH , United Kingdom.ORCID 0000-0002-8536-0130
Isabela RibeiroDrugs for Neglected Diseases Initiative (DNDi) , Chemin Louis-Dunant 15 , 1202 Genève , Switzerland.
Lynn L SilverLL Silver Consulting , New Jersey , United States.
Jen SouthernLancaster Institute for the Contemporary Arts (LICA), The LICA Building , Lancaster University , Lancaster LA1 4YW , United Kingdom.
Thomas SpangenbergGlobal Health Institute of Merck, Ares Trading S.A. , a subsidiary of Merck KGaA Darmstadt Germany , Route de Crassier 1 , 1262 Eysins , Switzerland.ORCID 0000-0002-5654-8919
Shyam SundarDepartment of Medicine, Institute of Medical Sciences , Banaras Hindu University , Varanasi 221005 , India.
Caitlin TaylorSAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Institute of Infectious Disease and Molecular Medicine and Wellcome Centre for Infectious Disease Research in Africa , University of Cape Town , Observatory, Cape Town 7925 , South Africa.
Wes Van VoorhisCenter for Emerging and Re-emerging Infectious Diseases (CERID) , University of Washington , MS 358061, 750 Republican Street , Rm E-606, Seattle , Washington 98109-4766 , United States.
Nicholas J WhiteMahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine , Mahidol University , 3/F, 60th Anniversary Chalermprakiat Building, 420/6 Rajvithi Road , Bangkok 10400, Thailand.
Susan WyllieWellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery , University of Dundee , Dundee DD1 5EH , United Kingdom.ORCID 0000-0001-8810-5605
Paul G WyattWellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery , University of Dundee , Dundee DD1 5EH , United Kingdom.ORCID 0000-0002-0397-245X
Ian H GilbertWellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery , University of Dundee , Dundee DD1 5EH , United Kingdom.ORCID 0000-0002-5238-1314

Funding

Drug Discovery for Chagas DiseaseR01AI147504 · NIAID · UNIVERSITY OF WASHINGTON · PI Frederick Simmons Buckner, Michael H Gelb · 2019 to 2026
$5.9M
Drug Discovery for Human African TrypanosomiasisR01AI106850 · NIAID · UNIVERSITY OF WASHINGTON · PI BUCKNER, FREDERICK SIMMONS, GELB, MICHAEL H · 2013 to 2017
$3.7M
NIAID NIH HHS R01 AI106850NIAID NIH HHS R01 AI147504Wellcome Trust 203134/Z/16/ZWellcome Trust 204672/Z/16/Z
6 · The paper itself

Abstract

In May 2019, the Wellcome Centre for Anti-Infectives Research (

Indexed as

Communicable Disease ControlCongresses as TopicCombined Modality TherapyCommunicable DiseasesDrug DiscoveryDrug Evaluation, PreclinicalHIV InfectionsHumansPovertyUnited Kingdom

Identifiers

PMID31808676
PMCPMC6958537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.