Evidence map›Paper›PMID 31808134›Full record

ArticleAnnals of nuclear medicine2020

Evaluation of the total distribution volume of

Victor Romanov, Kayako Isohashi, Galal Alobthani, Rouaa Beshr, Genki Horitsugi, Yasukazu Kanai, Sadahiro Naka, Tadashi Watabe, Eku Shimosegawa, Jun Hatazawa

Open access · hybridAbstract read
In one paragraph

Article in Annals of nuclear medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Quantification ofMedicinal research reviews · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Evaluating boron neutron capture therapy as a potential treatment for unresectable gastrointestinal stromal tumors.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Enzymatic synthesis of fluorinated compounds.Applied microbiology and biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Victor RomanovDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Yamada Oka 2-2, Suita, Osaka, 565-0871, Japan.
Kayako IsohashiDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Yamada Oka 2-2, Suita, Osaka, 565-0871, Japan.
Galal AlobthaniDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Yamada Oka 2-2, Suita, Osaka, 565-0871, Japan.
Rouaa BeshrDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Yamada Oka 2-2, Suita, Osaka, 565-0871, Japan.
Genki HoritsugiDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Yamada Oka 2-2, Suita, Osaka, 565-0871, Japan.
Yasukazu KanaiDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Yamada Oka 2-2, Suita, Osaka, 565-0871, Japan.
Sadahiro NakaDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Yamada Oka 2-2, Suita, Osaka, 565-0871, Japan.
Tadashi WatabeDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Yamada Oka 2-2, Suita, Osaka, 565-0871, Japan.
Eku ShimosegawaDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Yamada Oka 2-2, Suita, Osaka, 565-0871, Japan.
Jun HatazawaDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Yamada Oka 2-2, Suita, Osaka, 565-0871, Japan. hatazawa@tracer.med.osaka-u.ac.jp.
Osaka University · JP

Funding

Ministry of Education, Culture, Sports, Science and Technology 24591758
6 · The paper itself

Abstract

objectiveBoron neutron capture therapy (BNCT) is a noninvasive radiation therapy method for cancer treatment. In BNCT, 4-borono-2-[

methodsSix healthy volunteers were injected with

resultsThe Ichise MA2 model showed the best fit among all models. Akaike Information Criterion (AIC) was the lowest for the Ichise's MA2 in all regions (mean AIC value - 14.0) comparing to the other models (Logan plot mean AIC 31.4; Ichise MA1 model mean AIC - 4.2). Mean Vt values of the Ichise MA2 model ranged from 0.94 ± 0.14 ml/ml in the pancreas to 0.16 ± 0.02 ml/ml in the right lung. Estimated boron concentration for

conclusionThe TRAIL REGISTRY: The UMIN clinical trial number: UMIN000022850.

Indexed as

AdultBoron CompoundsBoron Neutron Capture TherapyDose-Response Relationship, RadiationFemaleFluorine RadioisotopesHealthy VolunteersHumansMaleMiddle AgedNeoplasmsPhenylalaninePositron Emission Tomography Computed Tomography4-boronophenylalanineBoron CompoundsFluorine-18Fluorine RadioisotopesPhenylalanineBoron concentrationBPAFBPATotal distribution volume

Identifiers

PMID31808134
PMCPMC7033086
OpenAlexW2993809406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.