ArticleJournal of general internal medicine2020
Coronary Artery Disease and Atherosclerotic Risk Factors in a Population-Based Study of Sudden Death.
Article in Journal of general internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ethnic Disparities in Cardiovascular Disease: A Comparative Analysis of Asian and Central Asian Populations.Journal of racial and ethnic health disparities · 2026Pooled it
- Ferroptosis in vascular injury of critically ill patients: implications of gut microbiota regulation.Frontiers in cellular and infection microbiology · 2026Review
- Time Trend Analysis of Comorbidities in Ankylosing Spondylitis: A Population-Based Study from 53,142 Hospitalizations in Poland.Journal of clinical medicine · 2024Article
- Fine particulate matter-sudden death association modified by ventricular hypertrophy and inflammation: a case-crossover study.Frontiers in public health · 2024Article
- Comparison of histopathological and triphenyl tetrazolium chloride test in diagnosing myocardial infarction: An autopsy study.F1000Research · 2024Article
- Differences in severity of diffuse and focal coronary stenosis between visual and quantitative assessment.Frontiers in cardiovascular medicine · 2024Article
- Cardiac Magnetic Resonance in Hypertensive Heart Disease: Time for a New Chapter.Diagnostics (Basel, Switzerland) · 2022Review
- Social Disparities among Sudden Death victims with HIV.AIDS and behavior · 2022Article
- Symptoms prior to sudden death.Resuscitation plus · 2021Article
- Variations in blood pressure control by medical comorbidities prior to sudden death.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Cross-Sectional Survey of Clinical Trials of Stem Cell Therapy for Heart Disease Registered at ClinicalTrials.gov.Frontiers in cardiovascular medicine · 2021Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundSudden death is a public health problem with major impact on society. Coronary artery disease (CAD) is believed to underlie 60-80% of these deaths. While deaths from CAD have decreased in the recent decades, sudden death rates remain unacceptably high.
objectiveWe aimed to assess the prevalence of CAD and its risk factors among 18-64-year-old adults in a population-based case registry of sudden deaths and compare them to a living population from the same geographical area.
designFrom 2013 to 2015, all sudden deaths among 18-64-year-old adults in Wake County, NC, were identified (n = 371). A comparison group was formed by randomly selecting individuals from an electronic health record repository of a major healthcare system in the area (N = 4218). MAIN MEASURES: Prevalence of CAD and its risk factors among cases of sudden death and living population across sex and age groups. Odds of sudden death associated with atherosclerotic risk factors and comorbidities. KEY
resultsCAD was present in 14.8% of sudden death cases. Among sudden death victims, most risk factors and comorbidities were more common in the older age group, except for obesity which was more common in younger cases, and diabetes which was equally prevalent in younger and older cases. Compared to living population, sudden death cases had higher prevalence of atherosclerotic risk factors across all gender and age groups. Sudden death cases had a numerically higher number of risk factors compared to living population, regardless of age group or presence of CAD.
conclusionsCoronary artery disease is not common among sudden death cases, but risk factors and comorbidities are prevalent. Our findings support the changing etiology of sudden death. In the absence of clinically diagnosed CAD, use of novel imaging modalities and biomarkers may identify high-risk individuals and lead to prevention of sudden death.
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