ArticleJournal of applied genetics2020
Efficiency of induction of Shiga-toxin lambdoid prophages in Escherichia coli due to oxidative and antibiotic stress depends on the combination of prophage and the bacterial strain.
Article in Journal of applied genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- The Effect of Mitomycin C on Induction of Shiga Toxin Production in Clinical STEC Isolates.Toxins · 2025Article
- Bacteriophage Challenges in Industrial Processes: A Historical Unveiling and Future Outlook.Pathogens (Basel, Switzerland) · 2024Review
- InducedFrontiers in microbiology · 2024Article
- Genomic and Phenotypic Characterization of Shiga Toxin-ProducingMicroorganisms · 2023Article
- Early genome erosion and internal phage-symbiont-host interaction in the endosymbionts of a cold-seep tubeworm.iScience · 2023Article
- Emerging applications of phage therapy and fecal virome transplantation for treatment of Clostridioides difficile infection: challenges and perspectives.Gut pathogens · 2023Review
- Article
- Influence of temperature and pH on induction of Shiga toxinFrontiers in microbiology · 2023Article
- Population dynamics of cross-protection against β-lactam antibiotics in droplet microreactors.Frontiers in microbiology · 2023Article
- Escherichia coli ST155 as a production-host of three different polyvalent phages and their characterisation with a prospect for wastewater disinfection.Scientific reports · 2022Article
- Global diversity and distribution of prophages are lineage-specific within the Ralstonia solanacearum species complex.BMC genomics · 2022Article
- Genomic analysis of a novel active prophage of Hafnia paralvei.Archives of virology · 2022Article
- Biological foundations of successful bacteriophage therapy.EMBO molecular medicine · 2022Review
- Extracellular vesicle formation in Lactococcus lactis is stimulated by prophage-encoded holin-lysin system.Microbial biotechnology · 2022Article
- Induction and Genomic Analysis of a Lysogenic Phage of Hafnia paralvei.Current microbiology · 2022Article
- The bacteriophage decides own tracks: When they are with or against the bacteria.Current research in microbial sciences · 2021Review
- A Metabolite ofJournal of the American Chemical Society · 2021Article
- Characterization of a Novel Bacteriophage Henu2 and Evaluation of the Synergistic Antibacterial Activity of Phage-Antibiotics.Antibiotics (Basel, Switzerland) · 2021Article
- Prophage in Phage Manufacturing: Is the Risk Overrated Compared to Other Therapies or Food?Antibiotics (Basel, Switzerland) · 2020Article
- Induction of the Stringent Response Underlies the Antimicrobial Action of Aliphatic Isothiocyanates.Frontiers in microbiology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
In the study presented here, we tested, how large a fraction of lysogenic culture was undergoing filamentation, which could indicate triggering of the SOS response or SOS-independent prophage induction that is also known to cause cell filamentation. Here, antibiotic stress was triggered by adding mitomycin C and oxidative stress was induced by hydrogen peroxide. Observation of bacterial cells under an optical microscope revealed more filamenting cells for lysogenic Escherichia coli than for strains not carrying a prophage. Moreover, the amount of filamenting cells depended not only on the stress agents used and the type of the prophage, but also on the host. During induction of the 933W prophage, the resulting phage titer and the amount of elongating cells were different when using E. coli O157:H7 EDL933 clinical isolate and the E. coli MG1655 laboratory strain. The amount of filamenting cells correlates well with the observed phage titers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.