Evidence map›Paper›PMID 31808055›Full record

ArticleJournal of cell communication and signaling2020

ADP exerts P2Y

Harika Vemulapalli, Samara Albayati, Viren C Patwa, Douglas G Tilley, Alexander Y Tsygankov, Elisabetta Liverani

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cell communication and signaling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Platelet P2YBritish journal of pharmacology · 2024
    Review
  3. The Signaling Pathway of the ADP Receptor P2YInternational journal of molecular sciences · 2023
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. P2YInternational journal of molecular sciences · 2020
    Review
  10. P2YFrontiers in pharmacology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Harika VemulapalliSol Sherry Thrombosis Research Center, Lewis Katz School of Medicine at Temple University, 3420 North Broad Street, Philadelphia, PA, 19140, USA.
Samara AlbayatiSol Sherry Thrombosis Research Center, Lewis Katz School of Medicine at Temple University, 3420 North Broad Street, Philadelphia, PA, 19140, USA.
Viren C PatwaCenter for Translational Medicine, Lewis Katz School of Medicine, Temple University, 3500 North Broad Street, Philadelphia, PA, USA.
Douglas G TilleyCenter for Translational Medicine, Lewis Katz School of Medicine, Temple University, 3500 North Broad Street, Philadelphia, PA, USA.
Alexander Y TsygankovSol Sherry Thrombosis Research Center, Lewis Katz School of Medicine at Temple University, 3420 North Broad Street, Philadelphia, PA, 19140, USA.
Elisabetta LiveraniSol Sherry Thrombosis Research Center, Lewis Katz School of Medicine at Temple University, 3420 North Broad Street, Philadelphia, PA, 19140, USA. eliliverani@temple.edu.ORCID http://orcid.org/0000-0001-5540-0456
Temple University · USTemple University Hospital · US

Funding

American Heart Association 16SDG26980003
6 · The paper itself

Abstract

Purinergic signaling plays a complex role in inflammation. Nucleotides released by T lymphocytes, endothelial cells, and platelets during inflammation induce cellular responses by binding to receptors that regulate intracellular signaling pathways. Previous studies have found that purinergic signaling can have both proinflammatory and anti-inflammatory effects, but the roles of specific pathways in specific cell types are poorly understood. We investigated the role of the P2Y

Indexed as

ADP-receptor P2Y12P2Y12 antagonistPurinergic signalingT lymphocytes

Identifiers

PMID31808055
PMCPMC7176780
OpenAlexW2994275368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.