Evidence map›Paper›PMID 31807978›Full record

ArticleIrish journal of medical science2020

Risk factors for potential drug-drug interactions in patients with chronic obstructive pulmonary disease.

Dobrivoje Stojadinovic, Radica Zivkovic Zaric, Slobodan Jankovic, Zorica Lazic, Ivan Cekerevac, Romana Susa

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Article in Irish journal of medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dobrivoje StojadinovicFaculty of Medical Sciences, University of Kragujevac, Svetozara Markovića, Street 69, Kragujevac, 34000, Serbia.
Radica Zivkovic ZaricFaculty of Medical Sciences, University of Kragujevac, Svetozara Markovića, Street 69, Kragujevac, 34000, Serbia. radica_zivkovic@yahoo.com.ORCID http://orcid.org/0000-0002-6305-5485
Slobodan JankovicFaculty of Medical Sciences, University of Kragujevac, Svetozara Markovića, Street 69, Kragujevac, 34000, Serbia.
Zorica LazicFaculty of Medical Sciences, University of Kragujevac, Svetozara Markovića, Street 69, Kragujevac, 34000, Serbia.
Ivan CekerevacFaculty of Medical Sciences, University of Kragujevac, Svetozara Markovića, Street 69, Kragujevac, 34000, Serbia.
Romana SusaClinical Center Kragujevac, Kragujevac, Serbia.
University of Kragujevac · RSClinical Centre of Kragujevac · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Potential drug-drug interactions (pDDIs) are especially frequent in patients with chronic obstructive pulmonary disease (COPD) who, if hospitalized, experience, on average 6.5 pDDIs on admission, and 7.2 on discharge. The aim of our study was to identify and analyze risk and/or protective factors for occurrence of pDDIs in hospitalized patients with COPD. Main outcome was occurrence of pDDIs in COPD patients ascertained by Medscape, Epocrates, and Micromedex interaction checkers. The most serious pDDIs (contraindicated/serious/major/use alternative) were found in 16 (22%), 8 (11%), and 35 (49%) patients, according to the Medscape, Epocrates, and Micromedex, respectively. The COPD patients who were prescribed more drugs (especially antiarrhythmic and anticoagulants), by several independent prescribers, and having more comorbidities, were more prone to experience a pDDI; the only protective factor against pDDIs was age of the patients. In conclusion, COPD patients with the abovementioned risk factors should have their therapy more intensely monitored for pDDIs.

Indexed as

AgedComorbidityCross-Sectional StudiesDrug InteractionsFemaleHumansMaleProspective StudiesPulmonary Disease, Chronic ObstructiveRisk FactorsChronic obstructive pulmonary diseaseDrug-drug interactionsHospitalized patientsInteraction checkers

Identifiers

PMID31807978
OpenAlexW2993621045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.