ReviewVirchows Archiv : an international journal of pathology2020
Subsequent development of histiocytic sarcoma and follicular lymphoma: cytogenetics and next-generation sequencing analyses provide evidence for transdifferentiation of early common lymphoid precursor-a case report and review of literature.
Review in Virchows Archiv : an international journal of pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Synchronous or collision solid neoplasms and lymphomas: A systematic review of 308 case reports.Medicine · 2022Pooled it
- Histiocytic sarcoma with a common clonal origin emerged after 33 years from B-cell precursor acute lymphoblastic leukemia.Journal of clinical and experimental hematopathology : JCEH · 2026Article
- Co-occurrence of angioimmunoblastic T-cell lymphoma and aggressive-refractory plasma-cell neoplasm: Two new cases and literature review.Clinical hematology international · 2026Article
- Synchronous clonally related anaplastic large cell lymphoma and malignant histiocytosis.Diagnostic pathology · 2025Article
- Nodal T-Cell Lymphoma Transdifferentiated from Mantle Cell Lymphoma with Epstein-Barr Virus Infection.Pathobiology : journal of immunopathology, molecular and cellular biology · 2025Article
- Case report: Histiocytic sarcoma as transdifferentiation of a marginal zone lymphoma-a case presentation based onFrontiers in oncology · 2025Article
- Long-Term Remission with Novel Combined Immune-Targeted Treatment for Histiocytic Sarcoma Accompanied by Follicular Lymphoma: Case Report and Literature Review.International journal of molecular sciences · 2024Review
- Divergent evolution of metachronous follicular lymphoma and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue from a common precursor.The Journal of pathology · 2023Article
- PAX5 P80R-mutated B-cell acute lymphoblastic leukemia with transformation to histiocytic sarcoma: clonal evolution assessment using NGS-based immunoglobulin clonality and mutation analysis.Virchows Archiv : an international journal of pathology · 2023Article
- Histiocytic Sarcoma Involving Cervical Vertebra: A Case Report and Review of the Literature.Brain sciences · 2022Article
- Review
- KRAS and RAS-MAPK Pathway Deregulation in Mature B Cell Lymphoproliferative Disorders.Cancers · 2022Review
- Review
- ALK-positive histiocytosis associated with chronic lymphocytic leukaemia/small lymphocytic lymphoma: a multitarget response under ibrutinib.Virchows Archiv : an international journal of pathology · 2021Article
- Article
- Case Report: Phenotypic Switch in High-Grade B-Cell Lymphoma WithFrontiers in oncology · 2021Article
- Spectrum of histiocytic neoplasms associated with diverse haematological malignancies bearing the same oncogenic mutation.The journal of pathology. Clinical research · 2021Article
- Histiocytic and dendritic cell neoplasms of the mediastinum.Mediastinum (Hong Kong, China) · 2020Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Histiocytic sarcoma (HS) is a rare aggressive hematologic neoplasm that can be associated with low-grade B cell lymphoma. The development of both neoplasms is currently being considered a transdifferentiation mechanism but remains elusive. We report the case of a 65-year-old patient with synchronous development of peritoneal/abdominal HS and grade 1-2 follicular lymphoma (FL). Cytogenetic analysis and targeted next-generation sequencing of both FL and HS tumors identified common genomic alterations such as IGH-BCL2 rearrangement, CREBBP and KMT2D, and aberrations of chromosomes 9q and 19q. However, only the HS tumor had a KRAS mutation while the lymph node involved by FL harbored a TNFAIP3 mutation and both tumors also showed distinct chromosomal alterations. This report strengthens the hypothesis of a common lymphoid progenitor which accumulates genetic alterations leading to two different hematologic malignant diseases with significantly distinct prognoses.
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Registered trials
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