ArticleMolecular genetics and genomics : MGG2020
Combined GWAS and QTL analysis for dissecting the genetic architecture of kernel test weight in maize.
Article in Molecular genetics and genomics : MGG, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Genome-Wide Meta-Analysis of QTLs Associated with Root Traits and Implications for Maize Breeding.International journal of molecular sciences · 2023Pooled it
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- A genome-wide association study unveils the genetic architecture of morphological and biomass partitioning traits in maize under iron-deficient stress.Scientific reports · 2026Article
- Genetic Dissection of Carotenoid Variation by Integrating Quantitative Trait Loci Mapping and Candidate Region Association Study in Sweet Corn.Plants (Basel, Switzerland) · 2025Article
- Cloning and function analysis ofPlant signaling & behavior · 2025Article
- Candidate genes for kernel ratio in maize identified via combined GWAS and QTL mapping across multiple environments.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Genome-wide association study and genomic selection of brace root traits related to lodging resistance in maize.Scientific reports · 2024Article
- Genome-wide association study and candidate gene identification for agronomic traits in 182 upward-growing fruits of C. frutescens and C. annuum.Scientific reports · 2024Article
- Article
- Harnessing the predicted maize pan-interactome for putative gene function prediction and prioritization of candidate genes for important traits.G3 (Bethesda, Md.) · 2024Article
- A Genome-Wide Association Study Reveals the Genetic Mechanisms of Nutrient Accumulation in Spinach.Genes · 2024Article
- GWAS and Meta-QTL Analysis of Yield-Related Ear Traits in Maize.Plants (Basel, Switzerland) · 2023Article
- Genetic dissection of thousand-seed weight in linseed (Frontiers in plant science · 2023Article
- Co-expression pan-network reveals genes involved in complex traits within maize pan-genome.BMC plant biology · 2022Article
- Combining datasets for maize root seedling traits increases the power of GWAS and genomic prediction accuracies.Journal of experimental botany · 2022Article
- Genome-Wide Association Study Reveals the Genetic Basis of Kernel and Cob Moisture Changes in Maize at Physiological Maturity Stage.Plants (Basel, Switzerland) · 2022Article
- Detection of a major QTL and development of KASP markers for seed weight by combining QTL-seq, QTL-mapping and RNA-seq in peanut.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Genomic resources of broomcorn millet: demonstration and application of a high-throughput BAC mapping pipeline.BMC genomic data · 2021Article
- Genome-wide association study reveals the genetic architecture of root hair length in maize.BMC genomics · 2021Article
- Breeding Potentials of Bambara Groundnut for Food and Nutrition Security in the Face of Climate Change.Frontiers in plant science · 2021Review
Corrections and comments
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Authors and funding
18 authors at 3 institutions in 1 country.
Funding
Abstract
Kernel weight in a unit volume is referred to as kernel test weight (KTW) that directly reflects maize (Zea mays L.) grain quality. In this study, an inter-mated B73 × Mo17 (IBM) Syn10 doubled haploid (DH) population and an association panel were used to identify loci responsible for KTW of maize across multiple environments. A total of 18 significant KTW-related single-nucleotide polymorphisms (SNPs) were identified using genome-wide association study (GWAS); they were closely linked to 12 candidate genes. In the IBM Syn10 DH population, linkage analysis detected 19 common quantitative trait loci (QTL), five of which were repeatedly detected among multiple environments. Several verified genes that regulate maize seed development were found in the confidence intervals of the mapped QTL and the LD regions of GWAS, such as ZmYUC1, BAP2, ZmTCRR-1, dek36 and ZmSWEET4c. Combined QTL mapping and GWAS identified one significant SNP that was co-identified in the both populations. Based on the co-localized SNP across the both populations, 17 candidate genes were identified. Of them, Zm00001d044075, Zm00001d044086, and Zm00001d044081 were further identified by candidate gene association study for KTW. Zm00001d044081 encodes homeobox-leucine zipper protein ATHB-4, which has been demonstrated to control apical embryo development in Arabidopsis. Our findings provided insights into the mechanism underlying maize KTW and contributed to the application of molecular-assisted selection of high KTW breeding in maize.
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