Evidence map›Paper›PMID 31807813›Full record

ArticleCellular and molecular life sciences : CMLS2020

Exotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesis.

Erik Romp, Vandana Arakandy, Jana Fischer, Christiane Wolz, Anke Siegmund, Bettina Löffler, Lorena Tuchscherr, Oliver Werz, Ulrike Garscha

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Updates on the Natural History and Clinical Characteristics of NSAID-ERD.The journal of allergy and clinical immunology. In practice · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Frontiers in immunology · 2022
    Article
  11. Article
  12. Candida albicans-induced leukotriene biosynthesis in neutrophils is restricted to the hyphal morphology.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  13. Article
  14. Article
  15. Gram-Negative BacteriaFrontiers in pharmacology · 2021
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Erik RompDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University Jena, Philosophenweg 14, 07743, Jena, Germany.
Vandana ArakandyInstitute of Medical Microbiology, University Hospital Jena, 07747, Jena, Germany.
Jana FischerDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University Jena, Philosophenweg 14, 07743, Jena, Germany.
Christiane WolzInterfaculty Institute of Microbiology and Infection Medicine, University of Tuebingen, 72076, Tuebingen, Germany.
Anke SiegmundInstitute of Medical Microbiology, University Hospital Jena, 07747, Jena, Germany.
Bettina LöfflerInstitute of Medical Microbiology, University Hospital Jena, 07747, Jena, Germany.
Lorena TuchscherrInstitute of Medical Microbiology, University Hospital Jena, 07747, Jena, Germany.
Oliver WerzDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University Jena, Philosophenweg 14, 07743, Jena, Germany.
Ulrike GarschaDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich-Schiller-University Jena, Philosophenweg 14, 07743, Jena, Germany. ulrike.garscha@uni-jena.de.ORCID http://orcid.org/0000-0002-3645-7833
Friedrich Schiller University Jena · DEJena University Hospital · DEUniversity of Tübingen · DE

Funding

Deutsche Forschungsgemeinschaft GA2101/2-1Deutsche Forschungsgemeinschaft SFB 1278 PolytargetDeutsche Forschungsgemeinschaft SFB-TR156International Leibnitz Research school for Microbial and Biomolecular Interaction NoneLeibniz Science Campus InfectoOptics SAS-2015-HKI-LWC
6 · The paper itself

Abstract

Massive neutrophil infiltration is an early key event in infectious inflammation, accompanied by chemotactic leukotriene (LT)B

Indexed as

AnimalsArachidonate 5-LipoxygenaseBacterial ToxinsCalciumEnzyme ActivationExotoxinsFoot DiseasesHEK293 CellsHemolysin ProteinsHumansLeukotrienesMiceMice, Inbred C57BLNeutrophilsOligopeptidesReceptors, LipoxinArachidonate 5-LipoxygenaseBacterial ToxinsCalciumExotoxinsHemolysin ProteinsLeukotrienesOligopeptidesReceptors, Lipoxinstaphylococcal alpha-toxinstaphylococcal delta toxintryptophyl-arginyl-tryptophyl-tryptophyl-tryptophyl-tryptophanamide5-LipoxygenaseExotoxinsLeukotrienePhenol-soluble modulinsStaphylococcus aureus

Identifiers

PMID31807813
PMCPMC11105070
OpenAlexW2994150916

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.