Evidence map›Paper›PMID 31807790›Full record

ReviewHerz2020

Biomarkers in primary prevention : Meaningful diagnosis based on biomarker scores?

Christian Schulte, Tanja Zeller

Abstract readReview
PubMed Publisher
In one paragraph

Review in Herz, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Cardiac Troponin T Release after Football 7 in Healthy Children and Adults.International journal of environmental research and public health · 2020
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Christian SchulteKlinik für Kardiologie, Universitäres Herz- und Gefäßzentrum Hamburg, Martinistraße 52, 20246, Hamburg, Germany.
Tanja ZellerKlinik für Kardiologie, Universitäres Herz- und Gefäßzentrum Hamburg, Martinistraße 52, 20246, Hamburg, Germany. t.zeller@uke.de.
German Centre for Cardiovascular Research · DEMedizinisches Versorgungszentrum Prof. Mathey, Prof. Schofer · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular (CV) risk assessment is based on the utilization of risk scores, enabling clinicians to estimate an individual's risk to develop CV pathologies and events. Such risk scores comprise classic CV risk factors such as smoking, diabetes, hypertension, and blood cholesterol levels. Recently, other CV biomarkers such as cardiac troponins have been suggested and evaluated as alternative biomarkers not only in the acute diagnostic setting of myocardial infarction, but also as markers for risk stratification in the general population. In this review, we summarize the current knowledge on biomarkers in the field of primary prevention in cardiovascular disease (CVD). Furthermore, we present potential alternative biomarker-based strategies for CV risk assessment. In this respect we provide an outlook on the potential use of genomic variation as well as circulating non-coding RNAs to complement current risk assessment strategies so as to further personalize risk stratification in CVD.

Indexed as

BiomarkersCardiovascular DiseasesHypertensionMyocardial InfarctionPrimary PreventionHumansRisk AssessmentRisk FactorsBiomarkersBlood lipidsCardiovascular diseaseRisk assessmentRisk factorsTroponin

Identifiers

PMID31807790
OpenAlexW2994548612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.