Evidence map›Paper›PMID 31807429›Full record

ReviewTranslational andrology and urology2019

Epidemiology and treatment modalities for the management of benign prostatic hyperplasia.

Soum D Lokeshwar, Benjamin T Harper, Eric Webb, Andre Jordan, Thomas A Dykes, Durwood E Neal, Martha K Terris, Zachary Klaassen

Registry-linked trialAbstract readReview
In one paragraph

Review in Translational andrology and urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05416606 (Transurethral Bipolar Enucleation and Resection of the Prostate Versus Open Prostatectomy for the Treatment of Benign Prostatic Hyperplasia), which is not on this map. Cited by 104 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05416606 nacompletednot on this mapstarted 2020, after this paper: background citation

Transurethral Bipolar Enucleation and Resection of the Prostate Versus Open Prostatectomy for the Treatment of Benign Prostatic Hyperplasia

TypeinterventionalSponsorHelwan UniversityRan2020 to 2022Enrolled64ConditionsBenign Prostatic HyperplasiaArmstransurethral bipolar enucleation and resection of the prostate, open surgical transvesical prostatectomy
3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Soum D LokeshwarDepartment of Medicine, Miller School of Medicine, University of Miami, Miami, FL, USA.
Benjamin T HarperDivision of Urology, Department of Surgery, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Eric WebbDivision of Urology, Department of Surgery, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Andre JordanDepartment of Medicine, Miller School of Medicine, University of Miami, Miami, FL, USA.
Thomas A DykesDivision of Urology, Charlie Norwood Veteran Affairs Medical Center, Augusta, GA, USA.
Durwood E NealDivision of Urology, Department of Surgery, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Martha K TerrisDivision of Urology, Department of Surgery, Medical College of Georgia, Augusta University, Augusta, GA, USA.
Zachary KlaassenDivision of Urology, Department of Surgery, Medical College of Georgia, Augusta University, Augusta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benign prostatic hyperplasia (BPH) is one of the most common conditions affecting men. BPH can lead to a number of symptoms for patients commonly referred to as lower urinary tract symptoms (LUTS). Over the last decade, increased modifiable risk factors, such as metabolic disease and obesity, have resulted in an increased incidence of BPH. This increasing incidence has brought about a multitude of treatment modalities in the last two decades. With so many treatment modalities available, physicians are tasked with selecting the optimal therapy for their patients. Current therapies can first be divided into medical or surgical intervention. Medical therapy for BPH includes 5-alpha-reductase inhibitors and alpha-blockers, or a combination of both. Surgical interventions include a conventional transurethral resection of the prostate (TURP), as well as newer modalities such as bipolar TURP, holmium laser enucleation of the prostate (HoLEP), Greenlight and thulium laser, and prostatic urethral lift (PUL). Emerging therapies in this field must also be further investigated for safety and efficacy. This narrative review attempts to consolidate current and emerging treatment options for BPH and highlights the need for additional investigation on optimizing treatment selection.

Indexed as

Benign prostatic hyperplasia (BPH)BPH epidemiologyfuture therapiesurologic surgery

Identifiers

PMID31807429
PMCPMC6842780

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.