Evidence map›Paper›PMID 31807403›Full record

ArticleBeilstein journal of nanotechnology2019

Use of data processing for rapid detection of the prostate-specific antigen biomarker using immunomagnetic sandwich-type sensors.

Camila A Proença, Tayane A Freitas, Thaísa A Baldo, Elsa M Materón, Flávio M Shimizu, Gabriella R Ferreira, Frederico L F Soares, Ronaldo C Faria, Osvaldo N Oliveira

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Beilstein journal of nanotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Camila A ProençaChemistry Department, Federal University of São Carlos, CP 676, São Carlos 13565-905, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-8438-4651
Tayane A FreitasChemistry Department, Federal University of São Carlos, CP 676, São Carlos 13565-905, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-2086-5576
Thaísa A BaldoChemistry Department, Federal University of São Carlos, CP 676, São Carlos 13565-905, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-3212-0571
Elsa M MaterónChemistry Department, Federal University of São Carlos, CP 676, São Carlos 13565-905, São Paulo, Brazil.
Flávio M ShimizuSão Carlos Institute of Physics, University of São Paulo, CP 369, São Carlos 13560-970, São Paulo, Brazil.
Gabriella R FerreiraCarlos Institute of Chemistry, University of São Paulo, São Carlos 13560-970, São Paulo, Brazil.
Frederico L F SoaresChemistry Department, Federal University of São Carlos, CP 676, São Carlos 13565-905, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-8555-2095
Ronaldo C FariaChemistry Department, Federal University of São Carlos, CP 676, São Carlos 13565-905, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-1094-9597
Osvaldo N OliveiraSão Carlos Institute of Physics, University of São Paulo, CP 369, São Carlos 13560-970, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of cancer using electroanalytical methods can be achieved at low cost and in rapid assays, but this may require the combination with data treatment for determining biomarkers in real samples. In this paper, we report an immunomagnetic nanoparticle-based microfluidic sensor (INμ-SPCE) for the amperometric detection of the prostate-specific antigen (PSA) biomarker, the data of which were treated with information visualization methods. The INμ-SPCE consists of eight working electrodes, reference and counter electrodes. On the working electrodes, magnetic nanoparticles with secondary antibodies with the enzyme horseradish peroxidase were immobilized for the indirect detection of PSA in a sandwich-type procedure. Under optimal conditions, the immunosensor could operate within a wide range from 12.5 to 1111 fg·L

Indexed as

cancer biomarkersinformation visualizationmagnetite nanoparticlesmicrofluidic devicesnanoarchitectonicssandwich-type immunosensorsscreen-printed electrodes

Identifiers

PMID31807403
PMCPMC6880837

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.