Evidence map›Paper›PMID 31807304›Full record

ArticleClinical kidney journal2019

Kidney transplantation: an attractive and cost-effective alternative for older patients? A cost-utility study.

Kristian Heldal, Karsten Midtvedt, Kjersti Lønning, Tor Iversen, Kjersti Helene Hernæs, Vasiliki Tsarpali, Anna Varberg Reisæter, Tomm Bernklev

Abstract read
In one paragraph

Article in Clinical kidney journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Mapping health-related quality of life after kidney transplantation by group comparisons: a systematic review.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021
    Pooled it
  3. Review
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  6. Age-Related Risk After Kidney Transplantation: A Comprehensive Analysis of Infection Burden, Graft Outcomes, and Mortality.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kristian HeldalClinic of Internal Medicine, Telemark Hospital Trust, Skien, Norway.ORCID 0000-0003-4427-9528
Karsten MidtvedtDepartment of Transplantation Medicine, Section of Nephrology, Oslo University Hospital, Oslo, Norway.
Kjersti LønningFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Tor IversenDepartment of Health Management and Health Economics, University of Oslo, Oslo, Norway.
Kjersti Helene HernæsResearch Support Services, Health Economics, Oslo University Hospital, Oslo, Norway.
Vasiliki TsarpaliClinic of Internal Medicine, Telemark Hospital Trust, Skien, Norway.
Anna Varberg ReisæterDepartment of Transplantation Medicine, Section of Nephrology, Oslo University Hospital, Oslo, Norway.
Tomm BernklevFaculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the elderly, kidney transplantation is associated with increased survival and improved health-related quality of life compared with dialysis treatment. We aimed to study the short-term health economic effects of transplantation in a population of elderly kidney transplant candidates.

methodsSelf-perceived health, quality-adjusted life years (QALYs) and costs were evaluated and compared 1 year before and 1 year after kidney transplantation in patients included in a single-centre prospective study of 289 transplant candidates ≥65 years of age.

resultsSelf-perceived health and QALYs both significantly improved after transplantation. At 1 year, the costs per QALY were substantially higher for transplantation (€88 100 versus €76 495), but preliminary analyses suggest a favourable long-term health economic effect.

conclusionsKidney transplantation in older kidney transplant recipients is associated with improved health but also with increased costs the first year after engraftment when compared with remaining on the waiting list. Any long-term cost-effectiveness needs to be confirmed in studies with longer observation times.

Indexed as

dialysiselderlykidney transplantationQALYquality of life

Identifiers

PMID31807304
PMCPMC6885668

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.