Evidence map›Paper›PMID 31807216›Full record

ArticleBeilstein journal of organic chemistry2019

Chemical tuning of photoswitchable azobenzenes: a photopharmacological case study using nicotinic transmission.

Lorenzo Sansalone, Jun Zhao, Matthew T Richers, Graham C R Ellis-Davies

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Beilstein journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Deuteration-Driven Photopharmacology: Deuterium-LabeledACS pharmacology & translational science · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lorenzo Sansalone *Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA.ORCID https://orcid.org/0000-0002-7215-0783
Jun Zhao *Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA.ORCID https://orcid.org/0000-0003-3663-1595
Matthew T RichersDepartment of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA.ORCID https://orcid.org/0000-0002-2036-8262
Graham C R Ellis-DaviesDepartment of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA.ORCID https://orcid.org/0000-0003-4179-5455
Icahn School of Medicine at Mount Sinai · US

Funding

PHOTOCHEMICAL REGULATION OF CALCIUM IN CELL PHYSIOLOGYR01GM053395 · NIGMS · OREGON HEALTH AND SCIENCE UNIVERSITY · PI ELLIS-DAVIES, GRAHAM · 1995 to 2020
$6.1M
Light-Driven Control of Neurons in Vitro and in VivoR35NS111600 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Graham Ellis-Davies · 2019 to 2026
$5.5M
NIGMS NIH HHS R01 GM053395NINDS NIH HHS R35 NS111600
6 · The paper itself

Abstract

We have developed photochromic probes for the nicotinic acetylcholine receptor that exploit the unique chemical properties of the tetrafluoroazobenzene (4FAB) scaffold. Ultraviolet light switching and rapid thermal relaxation of the metastable

Indexed as

acetylcholine receptorsbidirectionalphotoswitchable drugtetrafluoroazobenzenevisible light

Identifiers

PMID31807216
PMCPMC6880823
OpenAlexW2989856453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.