Evidence map›Paper›PMID 31807094›Full record

ReviewOpen access rheumatology : research and reviews2019

Review of environmental factors and juvenile idiopathic arthritis.

Daniel B Horton, Susan Shenoi

Open access · goldAbstract readReview
In one paragraph

Review in Open access rheumatology : research and reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. New Diagnoses of Juvenile Idiopathic Arthritis Early in the COVID-19 Pandemic: Analysis of a Large United States Commercial Insurance Database.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Autoimmunity: the neoantigen hypothesis.Frontiers in immunology · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Haptoglobin in Juvenile Idiopathic Arthritis.Pediatric rheumatology online journal · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Daniel B HortonDepartment of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.ORCID 0000-0002-1831-1339
Susan ShenoiDepartment of Pediatrics, Division of Pediatric Rheumatology, Seattle Children's Hospital and Research Center and University of Washington, Seattle, WA, USA.ORCID 0000-0002-2495-594X
Rutgers, The State University of New Jersey · USSeattle Children's Hospital · US

Funding

Drugs, Germs, and Joints: Antibiotics, Gut Microbiota, and Juvenile Idiopathic ArthritisK23AR070286 · NIAMS · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI HORTON, DANIEL BENJAMIN · 2016 to 2020
$909k
NIAMS NIH HHS K23 AR070286
6 · The paper itself

Abstract

Juvenile idiopathic arthritis is a common rheumatic disease that presents as chronic childhood arthritis. JIA is considered a multifactorial disease that may result from diverse genetic and environmental risk factors. A minority of the population-attributable risk of JIA is estimated to be due to familial factors. Thus, non-genetic or environmental factors likely account for a majority of the risk of developing JIA. Yet, while substantial data have linked environmental factors to the development of rheumatoid arthritis, similar evidence regarding JIA is sparse. This narrative review provides updates on recent literature about environmental factors that might influence the risk of developing JIA, including studies about potentially beneficial and harmful influences as well as factors with unclear effects.

Indexed as

antibioticsbreast feedingcesarean sectionenvironmental exposurejuvenile arthritisrisk factors

Identifiers

PMID31807094
PMCPMC6842741
OpenAlexW2988688687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.