Evidence map›Paper›PMID 31806982›Full record

ArticleVascular health and risk management2019

Marker Of Sepsis Severity Is Associated With The Variation In Cardio-Ankle Vascular Index (CAVI) During Sepsis Treatment.

Daiji Nagayama, Haruki Imamura, Kei Endo, Atsuhito Saiki, Yuta Sato, Takashi Yamaguchi, Yasuhiro Watanabe, Masahiro Ohira, Kohji Shirai, Ichiro Tatsuno

Open access · goldAbstract read
In one paragraph

Article in Vascular health and risk management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Daiji Nagayama *Nagayama Clinic, Tochigi, Japan.
Haruki Imamura *Center of Diabetes, Endocrinology and Metabolism, Toho University, Sakura Medical Center, Chiba, Japan.
Kei EndoEndo Clinic, Chiba, Japan.
Atsuhito SaikiCenter of Diabetes, Endocrinology and Metabolism, Toho University, Sakura Medical Center, Chiba, Japan.
Yuta SatoCenter of Diabetes, Endocrinology and Metabolism, Toho University, Sakura Medical Center, Chiba, Japan.
Takashi YamaguchiCenter of Diabetes, Endocrinology and Metabolism, Toho University, Sakura Medical Center, Chiba, Japan.
Yasuhiro WatanabeCenter of Diabetes, Endocrinology and Metabolism, Toho University, Sakura Medical Center, Chiba, Japan.
Masahiro OhiraCenter of Diabetes, Endocrinology and Metabolism, Toho University, Sakura Medical Center, Chiba, Japan.ORCID 0000-0002-1935-6125
Kohji ShiraiDepartment of Internal Medicine, Mihama Hospital, Chiba, Japan.
Ichiro TatsunoCenter of Diabetes, Endocrinology and Metabolism, Toho University, Sakura Medical Center, Chiba, Japan.ORCID 0000-0002-7200-7952
Toho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe main pathophysiology of sepsis is considered to be circulation crisis with an imbalance of vasodilation and vasoconstriction mechanisms, which contributes to multiple organ failure. However, sepsis-induced hemodynamic changes have not been fully validated by novel arterial stiffness parameter. The aim of this study was to clarify the acute vascular alteration and hemodynamic change in sepsis using cardio-ankle-vascular index (CAVI).

methodsTwenty-one Japanese patients (14 males and 7 females, age 62.8 ± 19.0 years) with sepsis were recruited. CAVI was measured before and 1-week after sepsis treatment.

resultsThe leading underlying cause of sepsis was pyelonephritis, followed by pneumonia, lung abscess, hepatic abscess and cholecystitis. All subjects recovered from sepsis. Analysis of all subjects showed a significant increase in CAVI after 1-week treatment (7.9 ± 2.4 to 9.6 ± 1.8, DISCUSSION: CAVI may reflect sepsis-induced vascular alteration which is not indicated by BP change, and is associated with sepsis severity. These findings suggest the usefulness of CAVI in the management of circulatory failure in sepsis patients.

Indexed as

Cardio Ankle Vascular IndexHemodynamicsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPredictive Value of TestsRecovery of FunctionSepsisSeverity of Illness IndexTime FactorsTreatment OutcomeVascular Stiffnessarterial stiffnesscirculation crisisprocalcitoninSIRS

Identifiers

PMID31806982
PMCPMC6842284
OpenAlexW2988633543

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.