Evidence map›Paper›PMID 31806960›Full record

ReviewInternational journal of nanomedicine2019

Advances in nanomedicine for the treatment of ankylosing spondylitis.

Yanhai Xi, Tingwang Jiang, Birendra Chaurasiya, Yanyan Zhou, Jiangmin Yu, Jiankun Wen, Yan Shen, Xiaojian Ye, Thomas J Webster

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
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  5. Article
  6. Nanotechnology applications in rheumatology.Rheumatology international · 2022
    Review
  7. Article
  8. Article
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  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Yanhai Xi *Department of Spine Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.ORCID 0000-0002-9276-7211
Tingwang Jiang *Department of Immunology and Microbiology, Institution of Laboratory Medicine of Changshu, Changshu, Jiangsu 215500, People's Republic of China.
Birendra ChaurasiyaDepartment of Pharmaceutics, Center for Research Development and Evaluation of Pharmaceutical Excipients and Generic Drugs, China Pharmaceutical University, Nanjing, People's Republic of China.ORCID 0000-0001-7243-1625
Yanyan ZhouDepartment of Spine Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Jiangmin YuDepartment of Spine Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Jiankun WenDepartment of Spine Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Yan ShenDepartment of Pharmaceutics, Center for Research Development and Evaluation of Pharmaceutical Excipients and Generic Drugs, China Pharmaceutical University, Nanjing, People's Republic of China.
Xiaojian YeDepartment of Spine Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Thomas J WebsterDepartment of Chemical Engineering, Northeastern University, Boston, MA, USA.ORCID 0000-0002-2028-5969
Second Military Medical University · CNChina Pharmaceutical University · CNChangshu No.1 People's Hospital · CNNortheastern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ankylosing spondylitis (AS) is a complex disease characterized by inflammation and ankylosis primarily at the cartilage-bone interface. The disease is more common in young males and risk factors include both genetic and environmental. While the pathogenesis of AS is not completely understood, it is thought to be an immune-mediated disease involving inflammatory cellular infiltrates, and human leukocyte antigen-B27. Currently, there is no specific diagnostic technique available for this disease; therefore conventional diagnostic approaches such as clinical symptoms, laboratory tests and imaging techniques are used. There are various review papers that have been published on conventional treatment approaches, and in this review work, we focus on the more promising nanomedicine-based treatment modalities to move this field forward.

Indexed as

AnalgesicsAnimalsAnti-Bacterial AgentsAntibodies, MonoclonalAnti-Inflammatory Agents, Non-SteroidalFemaleHumansHydrogelsLiposomesMaleNanomedicineNanoparticlesPhysical Therapy ModalitiesSpondylitis, AnkylosingTumor Necrosis Factor-alphaAnalgesicsAnti-Bacterial AgentsAntibodies, MonoclonalAnti-Inflammatory Agents, Non-SteroidalHydrogelsLiposomesTNF protein, humanTumor Necrosis Factor-alphaankylosing spondylitisenvironmental factorsgenetic factorspathogenesistreatment approaches

Identifiers

PMID31806960
PMCPMC6831987
OpenAlexW2982114154

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.