Evidence map›Paper›PMID 31806945›Full record

ArticleClinical interventions in aging2019

Relationship Between Potentially Inappropriate Medications And The Risk Of Hospital Readmission And Death In Hospitalized Older Patients.

Peng Wang, Qing Wang, Fang Li, Meng Bian, Kun Yang

Abstract read
In one paragraph

Article in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peng WangDepartment of Geriatrics, Fuxing Hospital, The Eighth Clinical Medical College, Capital Medical University, Beijing, People's Republic of China.ORCID 0000-0002-3743-4086
Qing WangDepartment of Geriatrics, Fuxing Hospital, The Eighth Clinical Medical College, Capital Medical University, Beijing, People's Republic of China.
Fang LiDepartment of Geriatrics, Fuxing Hospital, The Eighth Clinical Medical College, Capital Medical University, Beijing, People's Republic of China.
Meng BianDepartment of Pharmacy, Fuxing Hospital, The Eighth Clinical Medical College, Capital Medical University, Beijing, People's Republic of China.
Kun YangCentre for Evidence-Based Medicine, Xuanwu Hospital Capital Medical University, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to compare the prevalence of potentially inappropriate medications (PIMs) among hospitalized elderly patients using Beers and Chinese criteria and identify the correlation between PIMs and the risk of hospital readmission and death.

methodsThis study was conducted on geriatric patients aged ≥65 years at Beijing Fuxing Hospital between June 2015 and December 2017. The Beers criteria of 2015 and the Chinese criteria of 2017 were used to detect PIMs. Follow-ups were conducted for 12-36 months (or until patients' death, if it came sooner). Cox proportional-hazards models were used to explore the correlations between PIM use and the risk of hospital readmission and death.

resultsOf 508 patients, 352 (69.3%) and 339 (66.7%) had at least one PIM identified using the Beers criteria and the Chinese criteria, respectively. Proton-pump inhibitors in the Beers criteria and clopidogrel in the Chinese criteria were the most leading PIMs. PIMs identified using the Beers criteria were a risk factor for the all-cause hospital readmission. After adjusting for age, gender, comorbidity, and so forth, PIM use was still an indicator of rehospitalization. PIM grouping defined using the Chinese criteria was not associated with hospital readmission. PIM grouping defined using either criteria was not associated with all-cause death.

conclusionThe study showed a high prevalence of PIM use in China. PIMs defined using the Beers criteria increased the risk of hospital readmission. Clinicians should pay more attention to PIMs, carry out routine PIM assessment, and reduce adverse health outcomes in elderly patients.

Indexed as

AgedAged, 80 and overCause of DeathChinaFemaleHumansInappropriate PrescribingMalePatient ReadmissionPatient SafetyPolypharmacyPotentially Inappropriate Medication ListPrevalenceRisk FactorsBeers criteriaChinese criteriadeathelderlypotentially inappropriate medicationreadmission

Identifiers

PMID31806945
PMCPMC6839805

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.