ArticlePatient preference and adherence2019
Implication Of Character Traits In Adherence To Treatment In People With Gout: A Reason For Considering Nonadherence As A Syndrome.
Article in Patient preference and adherence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 7 citations in OpenAlex.
- Urate-lowering therapy adherence among gout patients in Southwest China: A cross-sectional study of determinants and regional disparities.Clinical rheumatology · 2026Article
- [Multidisciplinary expert consensus on tophus damage grading and surgical treatment (2025 edition)].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Article
- Psychosocial and clinical determinants of medication adherence among elderly chronic disease patients in China.Frontiers in pharmacology · 2026Article
- Tophus severity grading and surgical treatment: Chinese Medical Doctor Association Multidisciplinary Expert Consensus Statement and Recommendations, 2025.International journal of surgery (London, England) · 2026Article
- Determinants of Self-Management Behavior in Gout: A Scoping Review.Arthritis care & research · 2025Article
- Phenylketonuria as an Adherence Disease.Patient preference and adherence · 2025Review
- How is Patient Adherence Possible? A Novel Mechanistic Model of Adherence Based on Humanities.Patient preference and adherence · 2023Review
- An Unsafe/Safe Typology in People with Type 2 Diabetes: Bridging Patients' Expectations, Personality Traits, Medication Adherence, and Clinical Outcomes.Patient preference and adherence · 2022Article
- Intentionality in adherence to long-term therapies. Results from an online survey of 3,001 patients with cardio-metabolic pathologiesPatient preference and adherence · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveVarious aspects of nonadherence to therapy (including medication and lifestyle nonadherence) often appear together. Here we report the association between treatment adherence in gout and the two character traits of patience and obedience, which may explain this observation.
methodsData were collected from a cross-sectional study conducted in a French cohort of 1441 adult patients. Patience was assessed using the choice between receiving €1500 in 1 year or €500 immediately. Obedience was evaluated with a single question assessing the use of the seatbelt in the rear seat of a car. Adherence to recommendations for medication, beverage, food and physical activity and smoking status was assessed using self-report questionnaires.
resultsPatience and obedience were strong determinants of adherence to medication in multivariate analysis (OR 2.056, 95% CI [1.414-2.989],
conclusionCharacter traits, which shape preferences, may cause the clustering of different aspects of nonadherence in the form of a syndrome, elucidating the still enigmatic link between nonadherence to placebo and mortality in randomised clinical trials. This concept may also explain, at least in part, the difficulty of improving adherence to long-term therapies and may lead to ethical issues.
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