Evidence map›Paper›PMID 31806712›Full record

ArticleThe European respiratory journal2020

Early life exposure to air pollution and incidence of childhood asthma, allergic rhinitis and eczema.

Teresa To, Jingqin Zhu, Dave Stieb, Natasha Gray, Ivy Fong, Lauren Pinault, Michael Jerrett, Alain Robichaud, Richard Ménard, Aaron van Donkelaar and 4 more

Open access · hybridAbstract read
In one paragraph

Article in The European respiratory journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 7 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 7 syntheses or guidelines pooled it, 157 citations in OpenAlex.

  1. Pooled it
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  3. Association between air pollution and allergic upper respiratory diseases: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
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  7. The role of air pollution (PM and NOEnvironmental research · 2020
    Pooled it
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Teresa ToChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada teresa.to@sickkids.ca.
Jingqin ZhuChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada.
Dave StiebEnvironmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada.
Natasha GrayChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada.
Ivy FongChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada.ORCID 0000-0002-5132-7121
Lauren PinaultAnalytical Studies Branch, Statistics Canada, Ottawa, ON, Canada.
Michael JerrettFielding School of Public Health, The University of California, Los Angeles, CA, USA.
Alain RobichaudAir Quality Research Division, Environment and Climate Change Canada, Dorval, QC, Canada.
Richard MénardAir Quality Research Division, Environment and Climate Change Canada, Dorval, QC, Canada.
Aaron van DonkelaarDept of Physics and Atmospheric Science, Dalhousie University, Halifax, NS, Canada.
Randall V MartinDept of Physics and Atmospheric Science, Dalhousie University, Halifax, NS, Canada.ORCID 0000-0003-2632-8402
Perry HystadCollege of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA.
Jeffrey R BrookDalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Sharon DellChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada.
Hospital for Sick Children · CAUniversity of Toronto · CADalhousie University · CAEnvironment and Climate Change Canada · CAHealth Canada · CAOregon State University · USStatistics Canada · CAUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleThere is growing evidence that air pollution may contribute to the development of childhood asthma and other allergic diseases. In this follow-up of the Toronto Child Health Evaluation Questionnaire (T-CHEQ) study, we examined associations between early life exposures to air pollution and incidence of asthma, allergic rhinitis and eczema from birth through adolescence.

methods1286 T-CHEQ participants were followed from birth until outcome (March 31, 2016) or loss to follow-up, with a mean of 17 years of follow-up. Concentrations of nitrogen dioxide (NO

resultsHazard ratios of 1.17 (95% CI 1.05-1.31) for asthma and 1.07 (95% CI 0.99-1.15) for eczema were observed for total oxidants (O

conclusionsExposures to oxidant air pollutants (O

Indexed as

Air PollutantsAir PollutionAsthmaEczemaRhinitis, AllergicAdolescentChildEnvironmental ExposureHumansIncidenceInfant, NewbornNitrogen DioxideParticulate MatterAir PollutantsNitrogen DioxideParticulate Matter

Identifiers

PMID31806712
PMCPMC7031706
OpenAlexW2992180822

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.