Evidence map›Paper›PMID 31806659›Full record

ArticleDevelopment (Cambridge, England)2020

The PAX-SIX-EYA-DACH network modulates GATA-FOG function in fly hematopoiesis and human erythropoiesis.

T Michael Creed, Rajkumar Baldeosingh, Christian L Eberly, Caroline S Schlee, MinJung Kim, Jevon A Cutler, Akhilesh Pandey, Curt I Civin, Nancy G Fossett, Tami J Kingsbury

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Genetic research progress in branchioZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. RDGN-based predictive model for the prognosis of breast cancer.Experimental hematology & oncology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

T Michael CreedCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Rajkumar BaldeosinghCenter for Vascular and Inflammatory Diseases University of Maryland School of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Christian L EberlyCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Caroline S SchleeCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
MinJung KimCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Jevon A CutlerMcKusick-Nathans Institute of Genetic Medicine, Departments of Biological Chemistry, Oncology and Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Akhilesh PandeyMcKusick-Nathans Institute of Genetic Medicine, Departments of Biological Chemistry, Oncology and Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Curt I CivinCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Nancy G FossettCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA tkingsbury@som.umaryland.edu nfossett@gmail.com.ORCID 0000-0003-3575-7305
Tami J KingsburyCenter for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA tkingsbury@som.umaryland.edu nfossett@gmail.com.ORCID 0000-0003-3095-3788

Funding

The Nathan Schnaper Intern Program in Translational Cancer ResearchR25CA186872 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI BRET A HASSEL, Ian Robert Kleckner · 2015 to 2026
$3.0M
Genetic Regulation of Drosophila HematopoiesisR01DK072229 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI FOSSETT, NANCY G · 2005 to 2014
$2.7M
NCI NIH HHS R25 CA186872NIDDK NIH HHS R01 DK072229
6 · The paper itself

Abstract

The GATA and PAX-SIX-EYA-DACH transcriptional networks (PSEDNs) are essential for proper development across taxa. Here, we demonstrate novel PSEDN roles

Indexed as

Gene Regulatory NetworksAnimalsCell Line, TumorDrosophilaDrosophila ProteinsErythropoiesisGATA Transcription FactorsGene Knockout TechniquesHematopoiesisHomeodomain ProteinsHumansNerve Tissue ProteinsNuclear ProteinsPaired Box Transcription Factorsdac protein, DrosophilaDrosophila ProteinsFOG protein, DrosophilaGATA Transcription FactorsHomeodomain ProteinsNerve Tissue ProteinsNuclear ProteinsPaired Box Transcription FactorsSIX1 protein, humanSIX2 protein, humanGATAHematopoiesisPAX-SIX-EYA-DACH networkRetinal determination gene networkSIX1SIX2

Identifiers

PMID31806659
PMCPMC6983716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.