ArticleAJNR. American journal of neuroradiology2020
Visualization of Nigrosome 1 from the Viewpoint of Anatomic Structure.
Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Measuring the iron content of dopaminergic neurons in substantia nigra with MRI relaxometry.NeuroImage · 2021Article
- Evaluation of the Swallow-Tail Sign and Correlations of Neuromelanin Signal with Susceptibility and Relaxations.Tomography (Ann Arbor, Mich.) · 2021Article
- Article
- Do the Magic Angle Effects or Susceptibility Effects Affect the Visualization of Nigrosome 1?AJNR. American journal of neuroradiology · 2020Article
- Nigrosome and Neuromelanin Imaging as Tools to Differentiate Parkinson's Disease and Parkinsonism.Annals of Indian Academy of NeurologyArticle
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10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeParkinson disease is related to neurodegeneration and iron deposition in the substantia nigra pars compacta and nigrosome 1. However, visualization of nigrosome 1 via MR imaging is poor owing to the bilateral asymmetry, regardless of whether it is healthy. We focused on the magic angle and susceptibility effect and evaluated the anatomic slant structure of nigrosome 1 by tilting subjects' heads in the B MATERIALS AND
methodsTo investigate the effectiveness of the magic angle, we tilted the volunteers' heads to the right and left in the B
resultsThe heads tilted to the right and left showed significantly higher contrasts of nigrosome 1 and the substantia nigra pars compacta than the nontilted heads. No significant differences were observed in the visualization and susceptibility between the right nigrosome 1 and left nigrosome 1 for each head tilt. The effect of the magic angle was remarkable in the nontilted heads. This finding was supported by quantitative susceptibility mapping because the anatomic slant structure of nigrosome 1 was coherent between the axis of nigrosome 1 and the magic angle.
conclusionsThe asymmetric visualization of nigrosome 1 is affected by the magic angle and susceptibility. The anatomic slant structure of nigrosome 1 causes these challenges in visualization.
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