Evidence map›Paper›PMID 31806595›Full record

ArticleAJNR. American journal of neuroradiology2020

Dynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic Value.

I Hwang, S H Choi, C-K Park, T M Kim, S-H Park, J K Won, I H Kim, S-T Lee, R-E Yoo, K M Kang and 3 more

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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  9. AJNR. American journal of neuroradiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

I HwangFrom the Department of Radiology (I.H., S.H.C., R.-E.Y., K.M.K., T.J.Y., J.-H.K., C.-H.S.), Center for Nanoparticle Research.ORCID 0000-0002-1291-8973
S H ChoiFrom the Department of Radiology (I.H., S.H.C., R.-E.Y., K.M.K., T.J.Y., J.-H.K., C.-H.S.), Center for Nanoparticle Research verocay@snuh.org.ORCID 0000-0002-0412-2270
C-K ParkDepartment of Neurosurgery and Biomedical Research Institute (P.C.-K.).ORCID 0000-0002-2350-9876
T M KimDepartment of Internal Medicine and Cancer Research Institute (T.M.K.).ORCID 0000-0001-6145-4426
S-H ParkDepartment of Pathology (S.-H.P., J.K.W.).ORCID 0000-0002-8681-1597
J K WonDepartment of Pathology (S.-H.P., J.K.W.).ORCID 0000-0003-1459-8093
I H KimDepartment of Radiation Oncology and Cancer Research Institute (I.H.K.).ORCID 0000-0002-4755-5201
S-T LeeDepartment of Neurology (S.-T.L.), Seoul National University Hospital, Seoul, Korea.ORCID 0000-0003-4767-7564
R-E YooFrom the Department of Radiology (I.H., S.H.C., R.-E.Y., K.M.K., T.J.Y., J.-H.K., C.-H.S.), Center for Nanoparticle Research.ORCID 0000-0002-5625-5921
K M KangFrom the Department of Radiology (I.H., S.H.C., R.-E.Y., K.M.K., T.J.Y., J.-H.K., C.-H.S.), Center for Nanoparticle Research.ORCID 0000-0001-9643-2008
T J YunFrom the Department of Radiology (I.H., S.H.C., R.-E.Y., K.M.K., T.J.Y., J.-H.K., C.-H.S.), Center for Nanoparticle Research.ORCID 0000-0001-8441-4574
J-H KimFrom the Department of Radiology (I.H., S.H.C., R.-E.Y., K.M.K., T.J.Y., J.-H.K., C.-H.S.), Center for Nanoparticle Research.ORCID 0000-0002-6349-6950
C-H SohnFrom the Department of Radiology (I.H., S.H.C., R.-E.Y., K.M.K., T.J.Y., J.-H.K., C.-H.S.), Center for Nanoparticle Research.ORCID 0000-0003-0039-5746

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe prognostic value of dynamic contrast-enhanced MR imaging on nonenhancing T2 high-signal-intensity lesions in patients with glioblastoma has not been thoroughly elucidated to date. We evaluated the temporal change and prognostic value for progression-free survival of dynamic contrast-enhanced MR imaging-derived pharmacokinetic parameters on nonenhancing T2 high-signal-intensity lesions in patients with glioblastoma before and after standard treatment, including gross total surgical resection. MATERIALS AND

methodsThis retrospective study included 33 patients who were newly diagnosed with glioblastoma and treated with gross total surgical resection followed by concurrent chemoradiation therapy and adjuvant chemotherapy with temozolomide in a single institution. All patients underwent dynamic contrast-enhanced MR imaging before surgery as a baseline and after completion of maximal surgical resection and concurrent chemoradiation therapy. On the whole nonenhancing T2 high-signal-intensity lesion, dynamic contrast-enhanced MR imaging-derived pharmacokinetic parameters (volume transfer constant [

resultsBaseline median

conclusionsBaseline median

Indexed as

AdultAgedBrain NeoplasmsChemoradiotherapyContrast MediaFemaleGlioblastomaHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingPrognosisRadionuclide ImagingRetrospective StudiesContrast Media

Identifiers

PMID31806595
PMCPMC6975312

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.