Evidence map›Paper›PMID 31806592›Full record

ArticleAJNR. American journal of neuroradiology2019

Intracranial Atherosclerotic Burden on 7T MRI Is Associated with Markers of Extracranial Atherosclerosis: The SMART-MR Study.

M H T Zwartbol, M I Geerlings, R Ghaznawi, J Hendrikse, A G van der Kolk, UCC-SMART Study Group

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Intracranial vessel wall lesions on 7T MRI and MRI features of cerebral small vessel disease: The SMART-MR study.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  7. Article
  8. Article
  9. Reply.AJNR. American journal of neuroradiology · 2020
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

M H T ZwartbolFrom the Department of Radiology (M.H.T.Z., R.G., J.H., A.G.v.d.K.).ORCID 0000-0001-5779-3150
M I GeerlingsJulius Center for Health Sciences and Primary Care (M.I.G., R.G.), University Medical Center Utrecht and Utrecht University, Utrecht, the Netherlands. m.geerlings@umcutrecht.nl.ORCID 0000-0002-4037-036X
R GhaznawiFrom the Department of Radiology (M.H.T.Z., R.G., J.H., A.G.v.d.K.).ORCID 0000-0002-6616-5276
J HendrikseFrom the Department of Radiology (M.H.T.Z., R.G., J.H., A.G.v.d.K.).ORCID 0000-0001-6384-6140
A G van der KolkFrom the Department of Radiology (M.H.T.Z., R.G., J.H., A.G.v.d.K.).ORCID 0000-0002-8267-8848
UCC-SMART Study Group
Girls Incorporated · USUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIntracranial atherosclerosis, a major risk factor for ischemic stroke, is thought to have different atherogenic mechanisms than extracranial atherosclerosis. Studies investigating their relationship in vivo are sparse and report inconsistent results. We studied the relationship between intracranial atherosclerosis and extracranial atherosclerosis in a cohort of patients with a history of vascular disease. MATERIALS AND

methodsWithin the Second Manifestations of ARTerial disease-Magnetic Resonance (SMART) study, cross-sectional analyses were performed in 130 patients (mean age, 68 ± 9 years) with a history of vascular disease and with assessable 7T intracranial vessel wall MR imaging data. Intracranial atherosclerosis burden was defined as the number of intracranial vessel wall lesions in the circle of Willis and its major branches. Age- and sex-adjusted unstandardized regression coefficients (

resultsNinety-six percent of patients had ≥1 vessel wall lesion, with a mean intracranial atherosclerosis burden of 8.5 ± 5.7 lesions. Significant associations were observed between higher intracranial atherosclerosis burden and carotid intima-media thickness (

conclusionsIntracranial atherosclerosis was associated with various extracranial markers of atherosclerosis, not supporting a different etiology.

Indexed as

AgedAnatomy, Cross-SectionalAnkle Brachial IndexAtherosclerosisBiomarkersCarotid Intima-Media ThicknessCarotid StenosisCohort StudiesFemaleGlomerular Filtration RateHumansIntracranial ArteriosclerosisMagnetic Resonance ImagingMaleMiddle AgedRisk FactorsBiomarkers

Identifiers

PMID31806592
PMCPMC6975353
OpenAlexW2992126219

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.