ArticleSchizophrenia research2020
Duration of the psychosis prodrome.
Article in Schizophrenia research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- Neighborhood Characteristics and Social Functioning: Exploring Shared and Distinct Psychosocial Pathways Among Individuals at Clinical High-Risk for Psychosis.Schizophrenia bulletin · 2026Article
- Predictors and Moderators of Long-Term Outcome of Persons at Clinical High Risk for Psychosis: Methods and Preliminary Data.Schizophrenia bulletin · 2026Article
- Hallucinogen-Psychosis Associations Are Confounded by Baseline Psychiatric History.The Journal of clinical psychiatry · 2026Article
- Cannabis and tobacco co-use predicts psychosis in clinical high risk cohorts.Nature. Mental health · 2026Article
- Cannabis and Tobacco Co-Use Predicts Psychosis in Clinical High Risk Cohorts.medRxiv : the preprint server for health sciences · 2025Article
- Baseline Social Functioning Is Associated with Increased Likelihood of Remission from a Clinical High Risk for Psychosis Syndrome.Schizophrenia bulletin open · 2025Article
- A transdiagnostic prodrome for severe mental disorders: an electronic health record study.Molecular psychiatry · 2024Article
- Combinations and Temporal Associations Among Precursor Symptoms Before a First Episode of Psychosis.Schizophrenia bulletin · 2024Article
- Antecedents to first episode psychosis and mania: Comparing the initial prodromes of schizophrenia and bipolar disorder in a retrospective population cohort.Journal of affective disorders · 2023Article
- Towards a youth mental health paradigm: a perspective and roadmap.Molecular psychiatry · 2023Review
- Sampling from different populations: Sociodemographic, clinical, and functional differences between samples of first episode psychosis individuals and clinical high-risk individuals who progressed to psychosis.Schizophrenia research · 2023Article
- Machine Learning and Non-Affective Psychosis: Identification, Differential Diagnosis, and Treatment.Current psychiatry reports · 2022Review
- Early Intervention Services for Schizophrenia: Looking Back and Looking Ahead.Schizophrenia bulletin · 2022Article
- Full speed ahead on indicated prevention of psychosis.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021Article
- Predictive validity of conversion from the clinical high risk syndrome to frank psychosis.Schizophrenia research · 2020Article
- Evidence of Slow Neural Processing, Developmental Differences and Sensitivity to Cannabis Effects in a Sample at Clinical High Risk for Psychosis From the NAPLS Consortium Assessed With the Human Startle Paradigm.Frontiers in psychiatry · 2020Article
- Community Psychosis Risk Screening: An Instrument Development Investigation.Journal of psychiatry and brain science · 2020Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
The recognition of a prodromal period preceding the onset of frank psychosis dates back to its first descriptions. Despite insights gained from a prospective approach to the study of the Clinical High Risk syndrome for psychosis (CHR-P), a prospectively-based understanding of the duration of the psychosis prodrome and the factors that may influence is not well-established. Here we analyze data from the second North American Prodrome Longitudinal Study (NAPLS-2) to characterize prodrome duration in those who converted to psychosis. Of the 764 participants identified as being at CHR-P, 94 converted to psychosis and 92 of these had recorded estimates of prodrome onset. Estimates of prodrome duration were derived from CHR-P syndrome onset and conversion dates from the Structured Interview for Psychosis-risk Syndromes. Results identified a mean prodrome duration of 21.6 months. Neither CHR-P sub-syndrome nor medication exposure was found to significantly influence prodrome duration in this sample. These results provide the most precise estimate of prodrome duration to date, although results are limited to prodromes identified by ascertainment as being at CHR-P. Our findings also suggest a rule of thirds with regard to prodrome duration in those followed for two years: one third of CHR-P patients who convert will do so by 1 year after CHR-P syndrome onset, another third 1-2 years after onset, and the final third more than 2 years after onset.
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