ArticleBiomaterials2020
Evolution of metallic cardiovascular stent materials: A comparative study among stainless steel, magnesium and zinc.
Article in Biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 195 citations in OpenAlex.
- Bioresorbable magnesium flow diverter promotes early aneurysm occlusion in rabbits.Journal of neurointerventional surgery · 2026Article
- Advances in Functional Vascular Stents for Cardiovascular Therapy with Drug Delivery and Computational Design.Pharmaceutics · 2026Review
- Biodegradable Zn-Based Implants: Progress, Challenges, and Pathways toward Clinical Translation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Mechanically governed fracture resistance of biodegradable Zn-Cu alloy stents: Role of ring-length optimized structural design.Bioactive materials · 2026Article
- An Overview of Advanced Materials and Manufacturing Strategies for 3D-Printed Bioengineered Vascular Stents: Toward Next-Generation Drug Delivery Applications.Pharmaceutics · 2026Review
- Strut Thickness and Species-Specific Healing Are Key Considerations in Developing Zinc-Based Biodegradable Arterial Stents.Journal of biomedical materials research. Part B, Applied biomaterials · 2026Article
- Low addition of Er and Zn into biomedical magnesium with enhanced integrated properties for orthopedic applications:Bioactive materials · 2026Article
- Versatility of Click Chemistry in Hydrogel Synthesis: From Molecular Strategies to Applications in Regenerative Medicine.Gels (Basel, Switzerland) · 2026Review
- Preclinical research models for evaluating the biocompatibility of bioresorbable metallic cardiovascular stents: A comparative review.Bioactive materials · 2025Review
- Biodegradable Zinc-Based Alloys for Guided Bone Regeneration Membranes: Feasibility, Current Status, and Future Prospects.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Bonding of Hydrogel to Biometal Surfaces: Principles, Methods and Applications.Exploration (Beijing, China) · 2025Review
- Application of biodegradable implants in pediatric orthopedics: shifting from absorbable polymers to biodegradable metals.Bioactive materials · 2025Article
- Polymeric Nanomaterials for Atherosclerosis Diagnosis and Treatment.Polymer science & technology (Washington, D.C.) · 2025Review
- Evaluation of the interface of metallic-coated biodegradable polymeric stents with prokaryotic and eukaryotic cells.Bioactive materials · 2025Article
- Overview of porous magnesium-based scaffolds: development, properties and biomedical applications.Materials futures · 2025Review
- Advances in growth factor-containing 3D printed scaffolds in orthopedics.Biomedical engineering online · 2025Review
- Research progress on the role and mechanism of magnesium-containing materials in bone repair.Biomaterials translational · 2025Review
- MicroCT and contrast-enhanced microCT to study the in vivo degradation behavior and biocompatibility of candidate metallic intravascular stent materials.Acta biomaterialia · 2025Article
- Biodegradable high-nitrogen iron alloy anastomotic staples:Bioactive materials · 2024Article
- Long-term efficacy, safety and biocompatibility of a novel sirolimus eluting iron bioresorbable scaffold in a porcine model.Bioactive materials · 2024Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
A cardiovascular stent is a small mesh tube that expands a narrowed or blocked coronary artery. Unfortunately, current stents, regardless metallic or polymeric, still largely fall short to the ideal clinical needs due to late restenosis, thrombosis and other clinical complications. Nonetheless, metallic stents are preferred clinically thanks to their superior mechanical property and radiopacity to their polymeric counterparts. The emergence of bioresorbable metals opens a window for better stent materials as they may have the potential to reduce or eliminate late restenosis and thrombosis. In fact, some bioresorbable magnesium (Mg)-based stents have obtained regulatory approval or under trials with mixed clinical outcomes. Some major issues with Mg include the too rapid degradation rate and late restenosis. To mitigate these problems, bioresorbable zinc (Zn)-based stent materials are being developed lately with the more suitable degradation rate and better biocompatibility. The past decades have witnessed the unprecedented evolution of metallic stent materials from first generation represented by stainless steel (SS), to second generation represented by Mg, and to third generation represented by Zn. To further elucidate their pros and cons as metallic stent materials, we systematically evaluated their performances in vitro and in vivo through direct side-by-side comparisons. Our results demonstrated that tailored Zn-based material with proper configurations could be a promising candidate for a better stent material in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.