Evidence map›Paper›PMID 31806276›Full record

ArticleInternational journal of cardiology2020

Cardiometabolic responses to cardiac rehabilitation in people with and without diabetes.

Deepika R Laddu, Cemal Ozemek, Trina L Hauer, Codie R Rouleau, Tavis S Campbell, Stephen B Wilton, Sandeep Aggarwal, Leslie Austford, Ross Arena

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Deepika R LadduDepartment of Physical Therapy, University of Illinois at Chicago, Chicago, IL, USA. Electronic address: dladdu@uic.edu.
Cemal OzemekDepartment of Physical Therapy, University of Illinois at Chicago, Chicago, IL, USA.
Trina L HauerTotalCardiology™-Rehabilitation, Calgary, Alberta, Canada.
Codie R RouleauTotalCardiology™-Rehabilitation, Calgary, Alberta, Canada; Department of Psychology, University of Calgary, Calgary, Alberta, Canada.
Tavis S CampbellDepartment of Psychology, University of Calgary, Calgary, Alberta, Canada.
Stephen B WiltonLibin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada.
Sandeep AggarwalTotalCardiology™-Rehabilitation, Calgary, Alberta, Canada; Department of Psychology, University of Calgary, Calgary, Alberta, Canada; Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada.
Leslie AustfordTotalCardiology™-Rehabilitation, Calgary, Alberta, Canada.
Ross ArenaDepartment of Physical Therapy, University of Illinois at Chicago, Chicago, IL, USA.
Total (Canada) · CAUniversity of Illinois Chicago · USUniversity of Calgary · CALibin Cardiovascular Institute of Alberta · CA

Funding

The impact of a resistance training intervention on blood pressure control in older adults with SarcopeniaK01HL148503 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LADDU, DEEPIKA · 2019 to 2023
$901k
NHLBI NIH HHS K01 HL148503
6 · The paper itself

Abstract

backgroundType 2 diabetes and cardiometabolic comorbidities manifesting as the metabolic syndrome (MetS) are highly prevalent in coronary heart disease (CHD) patients attending cardiac rehabilitation (CR). The study aimed to determine the prevalence of cardiometabolic derangements and MetS, and compare post-CR clinical responses in a large cohort of CHD patients with and without diabetes.

methodsAnalyses were conducted on 3953 CHD patients [age: 61.1 ± 10.5 years; 741 (18.7%) with diabetes] that completed a representative 12-week CR program. A propensity model was used to match patients with diabetes (n = 731) to those without diabetes (n = 731) on baseline and clinical characteristics.

resultsDiabetic patients experienced smaller improvements in metabolic parameters after completing CR, including abdominal obesity, and lipid profiles (all P ≤ .002), compared to non-diabetic patients. For both groups, there were similar improvement rates in peak metabolic equivalents ([METs]; P < .001); however, peak METs remained lower at 12-weeks in patients with diabetes than without diabetes. At baseline, the combined prevalence of insulin resistance (IR) and diabetes was 57.3%, whereas IR was present in 48.2% of non-diabetic patients, of which rates were reduced to 48.2% and 32.8% after CR, respectively. Accordingly, MetS prevalence decreased from 25.5% to 22.3% in diabetic versus 20.0% to 13.4% in non-diabetic patients (all P ≤ .004).

conclusionsCompleting CR appears to provide comprehensive risk reduction in cardio-metabolic parameters associated with diabetes and MetS; however, CHD patients with diabetes may require additional and more aggressive attention towards all MetS criteria over the course of CR in order to prevent future cardiovascular events.

Indexed as

Coronary DiseaseDiabetes Mellitus, Type 2Metabolic SyndromeCardiac RehabilitationCardiorespiratory FitnessComorbidityExercise TherapyFemaleHumansInsulin ResistanceMaleMiddle AgedOutcome Assessment, Health CareRisk FactorsRisk Reduction BehaviorTreatment OutcomeCardiac rehabilitationCardiorespiratory fitnessCoronary artery diseaseDiabetes mellitusMetabolic syndrome

Identifiers

PMID31806276
PMCPMC7322825
OpenAlexW2991603635

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.