Evidence map›Paper›PMID 31806042›Full record

ArticleBMC research notes2019

Isolation and identification of Streptococcus suis from sick pigs in Bali, Indonesia.

I Nengah Kerta Besung, I Gusti Ketut Suarjana, Kadek Karang Agustina, Ida Bagus Oka Winaya, Hamong Soeharsono, Ni Ketut Suwiti, Gusti Ngurah Mahardika

Abstract read
In one paragraph

Article in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Current prevalence and therapeutic strategies for porcineApplied and environmental microbiology · 2025
    Review
  4. Article
  5. A large cluster of human infections ofOne health (Amsterdam, Netherlands) · 2022
    Article
  6. Sociocultural Factors Influencing HumanFoods (Basel, Switzerland) · 2022
    Review
  7. Article
  8. Neutrophils inMicroorganisms · 2021
    Review
  9. Microorganisms · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

I Nengah Kerta BesungLaboratory of Microbiology, Faculty of Veterinary Medicine, Udayana University of Bali, Jl. Sudirman, Denpasar, 80225, Indonesia. kerta_besung@unud.ac.id.ORCID http://orcid.org/0000-0002-5285-592X
I Gusti Ketut SuarjanaLaboratory of Microbiology, Faculty of Veterinary Medicine, Udayana University of Bali, Jl. Sudirman, Denpasar, 80225, Indonesia.
Kadek Karang AgustinaDepartment of Veterinary Public Health, Faculty of Veterinary Medicine, Udayana University of Bali, Jl. Sudirman, Denpasar, 80225, Indonesia.
Ida Bagus Oka WinayaLaboratory of Pathology, Faculty of Veterinary Medicine, Udayana University of Bali, Jl. Sudirman, Denpasar, 80225, Indonesia.
Hamong SoeharsonoLaboratory of Biochemistry, Faculty of Veterinary Medicine, Udayana University of Bali, Jl. Sudirman, Denpasar, 80225, Indonesia.
Ni Ketut SuwitiDepartment of Basic Veterinary Science, Faculty of Veterinary Medicine, Udayana University of Bali, Jl. Sudirman, Denpasar, 80225, Indonesia.
Gusti Ngurah MahardikaThe Animal Biomedical and Molecular Biology Laboratory, Udayana University of Bali, Jl. Sesetan-Markisa #6, Denpasar, 80226, Indonesia.

Funding

Kementerian Riset Teknologi Dan Pendidikan Tinggi Republik Indonesia 171.53/UN.14.4.A/LT/2018
6 · The paper itself

Abstract

objectiveStreptococcus suis (S. suis) is a causative agent for various syndromes in pigs. It can be transmitted to humans with typical symptoms of meningitis and death. Although human infections have been confirmed at Bali Referral Hospital, Indonesia, since 2014, the bacteria have not been isolated from pigs. Here, we provide confirmation of the presence of the bacteria in sick pigs in the province.

resultsStreptococcus suis was confirmed in 8 of 30 cases. The final confirmation was made using PCR and sequencing of the glutamate dehydrogenase (GDH) and recombination/repair protein (recN) gene fragments. Upon PCR serotyping, two were confirmed to be serotype 2 or 1/2. Prominent histopathological lesions of confirmed cases were meningitis, endocarditis, pericarditis, bronchopneumonia, enteritis and glomerulonephritis. The dominant inflammatory cells were neutrophils and macrophages. Further research is needed to understand the risk factors for human infection. Community awareness on the risk of contracting S. suis and vaccine development are needed to prevent human infections.

Indexed as

AnimalsGlutamate DehydrogenaseIndonesiaMolecular TypingPolymerase Chain ReactionStreptococcal InfectionsStreptococcus suisSwineSwine DiseasesGlutamate DehydrogenaseBaliGlutamate dehydrogenase (GDH) geneIndonesiaRecombination/repair protein (recN) geneSick pigsStreptococcus suis

Identifiers

PMID31806042
PMCPMC6896353

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.