ArticleBMC veterinary research2019
High levels of unreported intraspecific diversity among RNA viruses in faeces of neonatal piglets with diarrhoea.
Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- First molecular detection of porcine rotavirus B (RVB) in Poland - case study and genome analysis.Porcine health management · 2025Article
- Isothermal nucleic acid amplification assays for the detection of porcine stool-associated RNA virus.Scientific reports · 2025Article
- Genetic and Evolutionary Analysis of Porcine Kobuvirus in Guangxi Province, Southern China, Between 2021 and 2025.Microorganisms · 2025Article
- Seroepidemiology of Human Non-Species A Rotavirus Infections in Valencia, Spain.Journal of medical virology · 2025Article
- Extended analyses of rotavirus C (RVC) G-types and P-types reveal new cut-off value for the G-types and reclassification of strains.Journal of virology · 2025Article
- Relevancy Prediction of the Emerging Pathogens with Porcine Diarrhea by Logistic Regression Model.Microorganisms · 2025Article
- Severe Diarrhea Outbreaks in Newborn Piglets in China Associated With Porcine Rotavirus B.Transboundary and emerging diseases · 2025Article
- Exploring viral diversity in diarrheic porcine feces: a metagenomic analysis from an Indian swine farm.Frontiers in cellular and infection microbiology · 2025Article
- First Detection of a Novel Posavirus 2 Strain Identified from Pigs in China.Pathogens (Basel, Switzerland) · 2024Article
- Complete genome characterization by nanopore sequencing of rotaviruses A, B, and C circulating on large-scale pig farms in Russia.Virology journal · 2024Article
- A first report of rotavirus B from Zambian pigs leading to the discovery of a novel VP4 genotype P[9].Virology journal · 2024Article
- Phylogenetic Analyses of Rotavirus A, B and C Detected on a Porcine Farm in South Africa.Viruses · 2024Article
- Detection and genetic characterization of enteric viruses in diarrhoea outbreaks from swine farms in Spain.Porcine health management · 2023Article
- A Systematic Review: Is Porcine Kobuvirus Causing Gastrointestinal Disease in Young Pigs?Veterinary sciences · 2023Review
- Metatranscriptomic assessment of diarrhoeic faeces reveals diverse RNA viruses in rotavirus group A infected piglets and calves from India.Frontiers in cellular and infection microbiology · 2023Article
- The Complexity of Swine Caliciviruses. A Mini Review on Genomic Diversity, Infection Diagnostics, World Prevalence and Pathogenicity.Pathogens (Basel, Switzerland) · 2022Review
- Occurrence of Rotavirus A Genotypes and Other Enteric Pathogens in Diarrheic Suckling Piglets from Spanish Swine Farms.Animals : an open access journal from MDPI · 2022Article
- Diversity of respiratory viruses present in nasal swabs under influenza suspicion in respiratory disease cases of weaned pigs.Frontiers in veterinary science · 2022Article
- Molecular Survey on Kobuviruses in Domestic and Wild Ungulates From Northwestern Italian Alps.Frontiers in veterinary science · 2021Article
- Porcine sapoviruses: Pathogenesis, epidemiology, genetic diversity, and diagnosis.Virus research · 2020Review
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Authors and funding
11 authors.
Funding
Abstract
backgroundDiarrhoea is a major cause of death in neonate pigs and most of the viruses that cause it are RNA viruses. Next Generation Sequencing (NGS) deeply characterize the genetic diversity among rapidly mutating virus populations at the interspecific as well as the intraspecific level. The diversity of RNA viruses present in faeces of neonatal piglets suffering from diarrhoea in 47 farms, plus 4 samples from non-diarrhoeic piglets has been evaluated by NGS. Samples were selected among the cases submitted to the Veterinary Diagnostic Laboratories of Infectious Diseases of the Universitat Autònoma de Barcelona (Barcelona, Spain) and Universidad de León (León, Spain).
resultsThe analyses identified the presence of 12 virus species corresponding to 8 genera of RNA viruses. Most samples were co-infected by several viruses. Kobuvirus and Rotavirus were more commonly reported, with Sapovirus, Astrovirus 3, 4 and 5, Enterovirus G, Porcine epidemic diarrhoea virus, Pasivirus and Posavirus being less frequently detected. Most sequences showed a low identity with the sequences deposited in GenBank, allowing us to propose several new VP4 and VP7 genotypes for Rotavirus B and Rotavirus C.
conclusionsAmong the cases analysed, Rotaviruses were the main aetiological agents of diarrhoea in neonate pigs. Besides, in a small number of cases Kobuvirus and Sapovirus may also have an aetiological role. Even most animals were co-infected in early life, the association with enteric disease among the other examined viruses was unclear. The NGS method applied successfully characterized the RNA virome present in faeces and detected a high level of unreported intraspecific diversity.
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