ArticleBMC medical informatics and decision making2019
Improving reference prioritisation with PICO recognition.
Article in BMC medical informatics and decision making, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A comparative study of screening performance between abstrackr and GPT models: Systematic review and contextual analysis.BMC medical informatics and decision making · 2025Pooled it
- Large Language Model Analysis of Reporting Quality of Randomized Clinical Trial Articles: A Systematic Review.JAMA network open · 2025Pooled it
- Barriers and facilitators of HPV vaccination in sub-saharan Africa: a systematic review.BMC public health · 2023Pooled it
- Data extraction methods for systematic review (semi)automation: Update of a living systematic review.F1000Research · 2021Pooled it
- Methodological information extraction from randomized controlled trial publications: a pilot study.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2022Trial
- Natural Language Processing in Support of Evidence-based Medicine: A Scoping Review.Findings of ACL. ACL · 2025Article
- Icodec: A Novel Once-Weekly Basal Insulin for Diabetes Management.The Annals of pharmacotherapy · 2025Review
- Semi-supervised learning from small annotated data and large unlabeled data for fine-grained Participants, Intervention, Comparison, and Outcomes entity recognition.Journal of the American Medical Informatics Association : JAMIA · 2025Article
- SPIRIT-CONSORT-TM: a corpus for assessing transparency of clinical trial protocol and results publications.Scientific data · 2025Article
- SPIRIT-CONSORT-TM: a corpus for assessing transparency of clinical trial protocol and results publications.medRxiv : the preprint server for health sciences · 2025Article
- PICOT questions and search strategies formulation: A novel approach using artificial intelligence automation.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2025Article
- Text classification models for assessing the completeness of randomized controlled trial publications based on CONSORT reporting guidelines.Scientific reports · 2024Article
- Automation of systematic reviews of biomedical literature: a scoping review of studies indexed in PubMed.Systematic reviews · 2024Article
- Making guidelines computable.Clinical and public health guidelines · 2024Article
- CONSORT-TM: Text classification models for assessing the completeness of randomized controlled trial publications.medRxiv : the preprint server for health sciences · 2024Article
- Proton Pump Inhibitors in Pediatric Gastroesophageal Reflux Disease: A Systematic Review of Randomized Controlled Trials.Children (Basel, Switzerland) · 2024Review
- Not so weak PICO: leveraging weak supervision for participants, interventions, and outcomes recognition for systematic review automation.JAMIA open · 2023Article
- User experience of applying AMSTAR 2 to appraise systematic reviews of healthcare interventions: a commentary.BMC medical research methodology · 2023Article
- A Scoping Review of Adopted Information Extraction Methods for RCTs.Medical journal of the Islamic Republic of Iran · 2023Article
- PICO entity extraction for preclinical animal literature.Systematic reviews · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundMachine learning can assist with multiple tasks during systematic reviews to facilitate the rapid retrieval of relevant references during screening and to identify and extract information relevant to the study characteristics, which include the PICO elements of patient/population, intervention, comparator, and outcomes. The latter requires techniques for identifying and categorising fragments of text, known as named entity recognition.
methodsA publicly available corpus of PICO annotations on biomedical abstracts is used to train a named entity recognition model, which is implemented as a recurrent neural network. This model is then applied to a separate collection of abstracts for references from systematic reviews within biomedical and health domains. The occurrences of words tagged in the context of specific PICO contexts are used as additional features for a relevancy classification model. Simulations of the machine learning-assisted screening are used to evaluate the work saved by the relevancy model with and without the PICO features. Chi-squared and statistical significance of positive predicted values are used to identify words that are more indicative of relevancy within PICO contexts.
resultsInclusion of PICO features improves the performance metric on 15 of the 20 collections, with substantial gains on certain systematic reviews. Examples of words whose PICO context are more precise can explain this increase.
conclusionsWords within PICO tagged segments in abstracts are predictive features for determining inclusion. Combining PICO annotation model into the relevancy classification pipeline is a promising approach. The annotations may be useful on their own to aid users in pinpointing necessary information for data extraction, or to facilitate semantic search.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.