Evidence map›Paper›PMID 31805892›Full record

ArticleBMC pregnancy and childbirth2019

Initiation of antiretroviral therapy or antiretroviral prophylaxis in pregnant women living with HIV registered in five townships of Mandalay, Myanmar: A cross sectional study.

Khine Wut Yee Kyaw, Aye Aye Mon, Khaing Hnin Phyo, Nang Thu Thu Kyaw, Ajay M V Kumar, Than Than Lwin, Zaw Zaw Aung, Thet Ko Aung, Myo Minn Oo, Thurain Htun and 3 more

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Khine Wut Yee KyawDepartment of Operational Research, International Union Against Tuberculosis and Lung Disease (The Union), Mandalay, Myanmar. dr.khinewutyeekyaw2015@gmail.com.ORCID http://orcid.org/0000-0003-0709-484X
Aye Aye MonHIV unit, International Union Against Tuberculosis and Lung Disease (The Union), Mandalay, Myanmar.
Khaing Hnin PhyoHIV unit, International Union Against Tuberculosis and Lung Disease (The Union), Mandalay, Myanmar.
Nang Thu Thu KyawDepartment of Operational Research, International Union Against Tuberculosis and Lung Disease (The Union), Mandalay, Myanmar.
Ajay M V KumarCenter for Operational Research, International Union Against Tuberculosis and Lung Disease (The Union), Paris, France.
Than Than LwinNational AIDS Programme, Department of Public Health, Ministry of Health and Sports, Nay Pyi Taw, Myanmar.
Zaw Zaw AungNational AIDS Programme, Department of Public Health, Ministry of Health and Sports, Nay Pyi Taw, Myanmar.
Thet Ko AungHIV unit, International Union Against Tuberculosis and Lung Disease (The Union), Mandalay, Myanmar.
Myo Minn OoDepartment of Operational Research, International Union Against Tuberculosis and Lung Disease (The Union), Mandalay, Myanmar.
Thurain HtunMonitoring, Evaluation, Accountability and Learning Unit (HIV), International Union Against Tuberculosis and Lung Disease (The Union), Mandalay, Myanmar.
Sai Soe Thu YaMonitoring, Evaluation, Accountability and Learning Unit (HIV), International Union Against Tuberculosis and Lung Disease (The Union), Mandalay, Myanmar.
Srinath SatyanarayanaCenter for Operational Research, International Union Against Tuberculosis and Lung Disease (The Union), Paris, France.
Htun Nyunt OoNational AIDS Programme, Department of Public Health, Ministry of Health and Sports, Nay Pyi Taw, Myanmar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA series of interventions are required to prevent mother to child transmission (PMTCT) of Human Immunodeficiency Virus (HIV) starting from HIV testing of pregnant women, initiating antiretroviral therapy (ART) or antiretroviral prophylaxis to HIV-positive pregnant women to providing HIV prophylaxis to newborn babies. Gaps in each step can significantly affect the effectiveness of PMTCT interventions. We aimed to determine the gap in initiation of ART/antiretroviral prophylaxis for pregnant women living with HIV, delay in initiation of ART/antiretroviral prophylaxis and factors associated with the delay.

methodsThis is a cross sectional study using routinely collected programme data from five health facilities providing PMTCT services located at Township Health Departments (THD) of Mandalay, Myanmar.

resultsThere were 363 pregnant women living with HIV enrolled between January 2012 and December 2017. Sixty (16%) women were excluded from the study due to missing data on dates of HIV diagnosis. Of 303 (84%) women included in the study, 89/303 (29%) and 214/303 (71%) were diagnosed with HIV before and during current pregnancy respectively. Among 214 women, 180 (84%) women were started on ART by the censor date (31st March 2018). Among those who started ART, 109 (61%) women had a delay of starting ART > 2 weeks from diagnosis. Women residing in township 4 had a significantly higher risk of delay in initiation of ART/antiretroviral prophylaxis compared to women residing in township 1 [adjusted prevalence ratio 4.2 (95% confidence interval 1.2-14.8].

conclusionsWe found that one in four women living with HIV knew their HIV status before current pregnancy. Although the rate of ART/antiretroviral prophylaxis initiation was high among pregnant women living with HIV, there was a delay. Early initiation of ART/antiretroviral prophylaxis among newly HIV diagnosed pregnant women needs to be strengthened.

Indexed as

AdultAnti-Retroviral AgentsCross-Sectional StudiesFemaleHealth FacilitiesHIV InfectionsHumansInfectious Disease Transmission, VerticalMaternal Health ServicesMyanmarPregnancyPregnancy Complications, InfectiousRisk FactorsTime FactorsTime-to-TreatmentAnti-Retroviral AgentsHIVlinkageMyanmaroperational researchPMTCT

Identifiers

PMID31805892
PMCPMC6896496

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.