Evidence map›Paper›PMID 31805873›Full record

ArticleBMC genomics2019

Transcriptional profiling of skeletal muscle reveals starvation response and compensatory growth in Spinibarbus hollandi.

Yang Yang, Huiqiang Zhou, Liping Hou, Ke Xing, Hu Shu

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yang YangSchool of Life Science, Guangzhou University, Guangzhou, 510006, China.
Huiqiang ZhouSchool of Life Science, Guangzhou University, Guangzhou, 510006, China.
Liping HouSchool of Life Science, Guangzhou University, Guangzhou, 510006, China.
Ke XingSchool of Life Science, Guangzhou University, Guangzhou, 510006, China. xingk@mail.sysu.edu.cn.
Hu ShuSchool of Life Science, Guangzhou University, Guangzhou, 510006, China. shuhu001@126.com.
Guangzhou University · CN

Funding

Guangdong Provincial Science and Technology Program 2014A020208145National Public Industry Major Projects of China 201303048
6 · The paper itself

Abstract

backgroundSpinibarbus hollandi is an economically important fish species in southern China. This fish is known to have nutritional and medicinal properties; however, its farming is limited by its slow growth rate. In the present study, we observed that a compensatory growth phenomenon could be induced by adequate refeeding following 7 days of fasting in S. hollandi. To understand the starvation response and compensatory growth mechanisms in this fish, the muscle transcriptomes of S. hollandi under control, fasting, and refeeding conditions were profiled using next-generation sequencing (NGS) techniques.

resultsMore than 4.45 × 10

conclusionIn the present work, we reported the transcriptome profiles of S. hollandi muscle under different conditions. During fasting, the genes involved in the mobilization of stored energy were up-regulated, while the genes associated with growth were down-regulated. After refeeding, muscle hypertrophy contributed to the recovery of growth. The results of this study may help to elucidate the mechanisms underlying the starvation response and compensatory growth.

Indexed as

Gene Regulatory NetworksAnimalsCyprinidaeFastingFeeding BehaviorFish ProteinsGene Expression ProfilingGene Expression Regulation, DevelopmentalHigh-Throughput Nucleotide SequencingMuscle, SkeletalSequence Analysis, RNAFish ProteinsCompensatory growthMuscleSpinibarbus hollandiStarvation response

Identifiers

PMID31805873
PMCPMC6896686
OpenAlexW2993518544

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.