Evidence map›Paper›PMID 31805787›Full record

Trial reportCirculation. Cardiovascular quality and outcomes2019

Randomized Trial of an Intervention to Improve Blood Pressure Control in Stroke Survivors.

Mayowa O Owolabi, Mulugeta Gebregziabher, Rufus O Akinyemi, Joshua O Akinyemi, Onoja Akpa, Olanrewaju Olaniyan, Babatunde L Salako, Oyedunni Arulogun, Raelle Tagge, Ezinne Uvere and 2 more

Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Circulation. Cardiovascular quality and outcomes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01900756 (Tailored Hospital-based Risk Reduction to Impede Vascular Events After Stroke), which is not on this map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01900756 nacompletednot on this map

Tailored Hospital-based Risk Reduction to Impede Vascular Events After Stroke

TypeinterventionalSponsorMedical University of South CarolinaRan2014 to 2017Enrolled400ConditionsStrokeArmsTHRIVES
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  17. The African Stroke Organization Conference 2021: Building Capacity, Careers, Collaborations, and Contributions.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Mayowa O OwolabiDepartment of Medicine, University College Hospital and University of Ibadan, Nigeria and Center for Genomic and Precision Medicine, College of Medicine (M.O.O., R.O.A.), University of Ibadan, Nigeria.
Mulugeta GebregziabherDivision of Biostatistics and Bioinformatics, Department of Public Health Sciences (M.G.), Medical University of South Carolina.
Rufus O AkinyemiDepartment of Medicine, University College Hospital and University of Ibadan, Nigeria and Center for Genomic and Precision Medicine, College of Medicine (M.O.O., R.O.A.), University of Ibadan, Nigeria.
Joshua O AkinyemiDepartment of Epidemiology and Medical Statistics (J.O.A., O. Akpa), University of Ibadan, Nigeria.
Onoja AkpaDepartment of Epidemiology and Medical Statistics (J.O.A., O. Akpa), University of Ibadan, Nigeria.
Olanrewaju OlaniyanDepartment of Economics (O.O.), University of Ibadan, Nigeria.
Babatunde L SalakoDepartment of Medicine (B.L.S., E.U., A.F.), University of Ibadan, Nigeria.
Oyedunni ArulogunDepartment of Health Promotion and Education (O. Arulogun), University of Ibadan, Nigeria.
Raelle TaggeDepartment of Neurosciences (R.T.), Medical University of South Carolina.
Ezinne UvereDepartment of Medicine (B.L.S., E.U., A.F.), University of Ibadan, Nigeria.
Adekunle FakunleDepartment of Medicine (B.L.S., E.U., A.F.), University of Ibadan, Nigeria.
Bruce OvbiageleDepartment of Neurology, University of California, San Francisco (B.O.).
University College Hospital, Ibadan · NGUniversity of California, San Francisco · USUniversity of Ibadan · NG

Funding

Tailored Hospital-based Risk Reduction to Impede Vascular Events after Stroke (THU01NS079179 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI OVBIAGELE, BRUCE · 2012 to 2016
$2.1M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
NINDS NIH HHS R01 NS107900NINDS NIH HHS U01 NS079179
6 · The paper itself

Abstract

backgroundWe conducted the first-of-its kind randomized stroke trial in Africa to test whether a THRIVES (Tailored Hospital-based Risk reduction to Impede Vascular Events after Stroke) intervention improved blood pressure (BP) control among patients with stroke. METHODS AND

resultsIntervention comprised a patient global risk factor control report card, personalized phone text-messaging, and educational video. Four hundred patients recruited from 4 distinct medical facilities in Nigeria, aged ≥18 years with stroke-onset within one-year, were randomized to THRIVES intervention and control group. The control group also received text messages, and both groups received modest financial incentives. The primary outcome was mean change in systolic BP (SBP) at 12 months. There were 36.5% females, 72.3% with ischemic stroke; mean age was 57.2±11.7 years; 93.5% had hypertension and mean SBP was 138.33 (23.64) mm Hg. At 12 months, there was no significant difference in SBP reduction from baseline in the THRIVES versus control group (2.32 versus 2.01 mm Hg,

conclusionsTHRIVES intervention did not significantly reduce SBP compared with controls. However, there was similar significant decrease in mean BP in both treatment arms in the subgroup with baseline hypertension. As text-messaging and a modest financial incentive were the common elements between both treatment arms, further research is required to establish whether these measures alone can improve BP control among stroke survivors. CLINICAL

trial registrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT01900756.

Indexed as

Blood PressureHealth BehaviorHealth Knowledge, Attitudes, PracticeSelf CareAgedFemaleHumansHypertensionMaleMiddle AgedNigeriaPatient Education as TopicRisk FactorsStrokeText MessagingTime Factorsblood pressurehypertensionrisk factorsecondary preventionstroke

Identifiers

PMID31805787
PMCPMC7139215
OpenAlexW2991703740

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.