Evidence map›Paper›PMID 31805744›Full record

ArticleMicroorganisms2019

Oral Microbiota Composition and Antimicrobial Antibody Response in Patients with Recurrent Aphthous Stomatitis.

Zuzana Stehlikova, Vojtech Tlaskal, Natalie Galanova, Radka Roubalova, Jakub Kreisinger, Jiri Dvorak, Petra Prochazkova, Klara Kostovcikova, Jirina Bartova, Marketa Libanska and 10 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. [Research Advances on Natural Products in Maintaining Oral Microecological Balance].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Frontiers in cellular and infection microbiology · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Zuzana StehlikovaInstitute of Microbiology of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Vojtech TlaskalInstitute of Microbiology of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Natalie GalanovaInstitute of Microbiology of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Radka RoubalovaInstitute of Microbiology of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Jakub KreisingerDepartment of Zoology, Faculty of Science, Charles University, 128 00 Prague, Czech Republic.
Jiri DvorakInstitute of Microbiology of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Petra ProchazkovaInstitute of Microbiology of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Klara KostovcikovaInstitute of Microbiology of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Jirina BartovaInstitute of Dental Medicine, Department of Oral Medicine, General University Hospital in Prague, 128 00 Prague, Czech Republic.
Marketa LibanskaInstitute of Dental Medicine, Department of Oral Medicine, General University Hospital in Prague, 128 00 Prague, Czech Republic.
Radka CermakovaInstitute of Dental Medicine, Department of Oral Medicine, General University Hospital in Prague, 128 00 Prague, Czech Republic.
Dagmar SchierovaInstitute of Animal Physiology and Genetics of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Antonin FassmannClinic of Dentistry, St. Anne's Faculty Hospital, 656 91, Brno, Czech Republic.
Petra Borilova LinhartovaClinic of Dentistry, St. Anne's Faculty Hospital, 656 91, Brno, Czech Republic.
Stepan CoufalInstitute of Microbiology of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Miloslav KverkaInstitute of Microbiology of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Lydie Izakovicova-HollaClinic of Dentistry, St. Anne's Faculty Hospital, 656 91, Brno, Czech Republic.
Jitka PetanovaInstitute of Immunology and Microbiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 00 Prague, Czech Republic.
Helena Tlaskalova-HogenovaInstitute of Microbiology of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Zuzana Jiraskova ZakostelskaInstitute of Microbiology of the CAS, v.v.i., 142 20 Prague, Czech Republic.
Czech Academy of Sciences, Institute of Microbiology · CZCharles University · CZGeneral University Hospital in Prague · CZMasaryk University · CZCzech Academy of Sciences, Institute of Animal Physiology and Genetics · CZ

Funding

Grant Agency of Charles University GAUK 1366217Grant Agency of Charles University GAUK 908217Ministry of Health of the Czech Republic 15-29336A
6 · The paper itself

Abstract

Recurrent aphthous stomatitis (RAS) is the most common disease of the oral mucosa, and it has been recently associated with bacterial and fungal dysbiosis. To study this link further, we investigated microbial shifts during RAS manifestation at an ulcer site, in its surroundings, and at an unaffected site, compared with healed mucosa in RAS patients and healthy controls. We sampled microbes from five distinct sites in the oral cavity. The one site with the most pronounced differences in microbial alpha and beta diversity between RAS patients and healthy controls was the lower labial mucosa. Detailed analysis of this particular oral site revealed strict association of the genus

Indexed as

microbiomemycobiomeoral mucosa

Identifiers

PMID31805744
PMCPMC6955784
OpenAlexW2991055957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.