Evidence map›Paper›PMID 31805707›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Biophysical Characterization of (Silica-coated) Cobalt Ferrite Nanoparticles for Hyperthermia Treatment.

Niklas Lucht, Ralf P Friedrich, Sebastian Draack, Christoph Alexiou, Thilo Viereck, Frank Ludwig, Birgit Hankiewicz

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Niklas LuchtInstitute of Physical Chemistry, Universität Hamburg, Grindelallee 117, 20146 Hamburg, Germany.
Ralf P FriedrichDepartment of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Professorship, Universitätsklinikum Erlangen, Glückstraße 10a, 91054 Erlangen, Germany.
Sebastian DraackInstitute for Electrical Measurement Science and Fundamental Electrical Engineering, Technical University of Braunschweig, Hans-Sommer-Straße 66, 38106 Braunschweig, Germany.ORCID 0000-0003-2030-5269
Christoph AlexiouDepartment of Otorhinolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung-Professorship, Universitätsklinikum Erlangen, Glückstraße 10a, 91054 Erlangen, Germany.
Thilo ViereckInstitute for Electrical Measurement Science and Fundamental Electrical Engineering, Technical University of Braunschweig, Hans-Sommer-Straße 66, 38106 Braunschweig, Germany.ORCID 0000-0001-6814-6266
Frank LudwigInstitute for Electrical Measurement Science and Fundamental Electrical Engineering, Technical University of Braunschweig, Hans-Sommer-Straße 66, 38106 Braunschweig, Germany.ORCID 0000-0002-2476-1352
Birgit HankiewiczInstitute of Physical Chemistry, Universität Hamburg, Grindelallee 117, 20146 Hamburg, Germany.

Funding

Deutsche Forschungsgemeinschaft AL 552/5-3Deutsche Forschungsgemeinschaft FI 1235/2-2Deutsche Forschungsgemeinschaft VI 892/1-1
6 · The paper itself

Abstract

Magnetic hyperthermia is a technique that describes the heating of material through an external magnetic field. Classic hyperthermia is a medical condition where the human body overheats, being usually triggered by a heat stroke, which can lead to severe damage to organs and tissue due to the denaturation of cells. In modern medicine, hyperthermia can be deliberately induced to specified parts of the body to destroy malignant cells. Magnetic hyperthermia describes the way that this overheating is induced and it has the inherent advantage of being a minimal invasive method when compared to traditional surgery methods. This work presents a particle system that offers huge potential for hyperthermia treatments, given its good loss value, i.e., the particles dissipate a lot of heat to their surroundings when treated with an ac magnetic field. The measurements were performed in a low-cost custom hyperthermia setup. Additional toxicity assessments on Jurkat cells show a very low short-term toxicity on the particles and a moderate low toxicity after two days due to the prevalent health concerns towards nanoparticles in organisms.

Indexed as

hyperthermiaInductionmagnetic fluidsmagnetismtoxicity

Identifiers

PMID31805707
PMCPMC6956109

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.