Evidence map›Paper›PMID 31805687›Full record

ArticleCancers2019

Monitoring Patients with Metastatic Hormone-Sensitive and Metastatic Castration-Resistant Prostate Cancer: A Multidisciplinary Consensus Document.

Alberto Lapini, Orazio Caffo, Giovanni Pappagallo, Roberto Iacovelli, Rolando Maria D'Angelillo, Vittorio Vavassori, Roberta Ceccarelli, Sergio Bracarda, Barbara Alicja Jereczek-Fossa, Luigi Da Pozzo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Radiographic Progression With and Without Prostate-Specific Antigen Rise in Patients With Advanced Prostate Cancer Treated With Enzalutamide.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026
    Trial
  3. Review
  4. Article
  5. Observational
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Alberto LapiniDepartment of Urology, University of Florence, University Hospital, 50134 Florence, Italy.
Orazio CaffoDepartment of Medical Oncology, Santa Chiara Hospital, 38112 Trento, Italy.
Giovanni PappagalloItalian Society of Uro-Oncology, 40125 Bologna, Italy.
Roberto IacovelliDepartment of Medical Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Rolando Maria D'AngelilloRadiotherapy Unit, Campus Bio-Medico University, 00128 Rome, Italy.
Vittorio VavassoriDepartment of Radiation Oncology, Humanitas Gavazzeni, 24125 Bergamo, Italy.
Roberta CeccarelliItalian Society of Uro-Oncology, 40125 Bologna, Italy.
Sergio BracardaDepartment of Medical Oncology, "Santa Maria" Hospital,05100 Terni, Italy.
Barbara Alicja Jereczek-FossaDepartment of Oncology and Hemato-oncology, University of Milan, Division of Radiotherapy, IEO European Institute of Oncology, IRCCS, 20132 Milan, Italy.
Luigi Da PozzoDepartment of Urology, Università degli Studi Milano Bicocca - ASST Papa Giovanni XXIII, 24129 Bergamo, Italy.
Giario Natale ContiUrology Unit, Azienda Socio-Sanitaria Territoriale Lariana, Sant'Anna Hospital, 22042 Como, Italy.
Agostino Gemelli University Polyclinic · ITAzienda Socio Sanitaria Territoriale Lariana · ITHumanitas Gavazzeni · ITOspedale Papa Giovanni XXIII · ITOspedale Santa Chiara · ITSanta Maria Nuova Hospital · ITUniversità Campus Bio-Medico · ITUniversity of Florence · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe availability of a number of agents that are efficacious in patients with metastatic prostate cancer (mPC) has led to them being used sequentially, and this has prolonged patient survival. However, in order to maximize their efficacy, clinicians need to be able to obtain a reliable picture of disease evolution by means of monitoring procedures.

methodsAs the intensive monitoring protocols used in pivotal trials cannot be adopted in everyday clinical practice and there is no agreement among the available guidelines, a multidisciplinary panel of Italian experts met to develop recommendations for monitoring mPC patients using a modified Delphi method.

resultsThe consensus project considered methods of clinically, radiographically, and biochemically monitoring patients with metastatic hormone-sensitive and metastatic castration-resistant prostate cancer undergoing chemotherapy and/or hormonal treatment. The panelists also considered the methods and timing of monitoring castration levels, bone health, and the metabolic syndrome during androgen deprivation therapy.

conclusionsThe recommendations, which were drawn up by experts following a formal and validated consensus procedure, will help clinicians face the everyday challenges of monitoring metastatic prostate cancer patients.

Indexed as

castration-resistant prostate cancercastration-sensitive prostate cancerconsensus conferencemonitoring procedures

Identifiers

PMID31805687
PMCPMC6966424
OpenAlexW2991348708

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.