ArticlePsychoneuroendocrinology2020
Going the distance: The diurnal range of cortisol and its association with cognitive and physiological functioning.
Article in Psychoneuroendocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Linking epigenetic age acceleration to self-reported daily memory lapses: evidence from the National Study of Daily Experiences.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Strain and recovery activities over a week predict short-term changes in processing speed measured in everyday environments: A survey response-time study in workers from a large internet panel.Neuropsychology · 2026Article
- Article
- Maternal cortisol and parenting in infants' first 6 months: The moderating role of family stress.Developmental psychology · 2026Article
- Loneliness, positive social interactions, and diurnal cortisol among mid-to-later life adults in everyday life.Biological psychology · 2026Article
- A Community-Engaged Approach for Assessment of Cortisol Dynamic Range and Multilevel Chronic Stress in African Americans: FAITH! Heart Health+ Ancillary Study.Journal of participatory medicine · 2025Article
- Effects of Sociospatial Inequality on Exposure to Stress, Symptoms of Depression, and Cortisol Rhythms in Pregnancy.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN · 2025Observational
- Reduction in SH-SY5Y Cell Stress Induced by Corticosterone and Attenuation of the Inflammatory Response in RAW 264.7 Cells Using Endomorphin Analogs.Biomedicines · 2025Article
- The energetic stress cytokine GDF15 is elevated in the context of chronic and acute psychosocial stress.bioRxiv : the preprint server for biology · 2025Article
- Daily Stress and Cortisol Patterns in Midlife and Older Parents of Children With Developmental Disabilities.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Measuring salivary cortisol in biobehavioral research: A systematic review and methodological considerations.Brain, behavior, & immunity - health · 2025Review
- Perinatal Predictors and Mediators of Attachment Patterns in Preschool Children: Exploration of Children's Contributions in Interactions with Mothers.Children (Basel, Switzerland) · 2024Article
- Cortisol's diurnal rhythm indexes the neurobiological impact of child adversity in adolescence.Biological psychology · 2024Article
- Do diurnal salivary cortisol curves carry meaningful information about the regulatory biology of the HPA axis in healthy humans?Psychoneuroendocrinology · 2023Article
- Targeting the Arginine Vasopressin VNeuropsychiatric disease and treatment · 2023Review
- Immunological routine laboratory parameters at admission influence the improvement of positive symptoms in schizophrenia patients after pharmacological treatment.Frontiers in psychiatry · 2023Article
- Allostatic Load and Cognitive Function Among Urban Adults in the Healthy Aging in Neighborhoods of Diversity across the Life Span Study.Journal of Alzheimer's disease : JAD · 2023Article
- Cortisol and cardiometabolic disease: a target for advancing health equity.Trends in endocrinology and metabolism: TEM · 2022Review
- Genomic-Analysis-Oriented Drug Repurposing in the Search for Novel Antidepressants.Biomedicines · 2022Article
- Advancing health equity through integrated biology and population health research: A community-based sample cortisol feasibility and exploratory study.Comprehensive psychoneuroendocrinology · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Cortisol features prominently in theories describing how chronic stress wears away at physical and cognitive health. The current study examines composite measures of physiological and cognitive functioning in relation to two aspects of daily cortisol: total daily output and change in levels throughout the day. Participants (N = 1001; aged 28-84 years-old) from the Midlife Development in the United States (MIDUS) study provided 4 daily saliva samples across four consecutive days and underwent a physical exam that provided information about six inter-related physiological systems that were combined into a measure of allostatic load. They also completed a phone-based battery of cognitive tasks, which provided a composite score combining memory, reasoning, and speed of processing performance. Total daily cortisol output was captured using area under the curve with respect to ground (AUCg). Change in cortisol levels was assessed using two methods: slope, calculated through piecewise spline models, and dynamic range, calculated by the difference between the day's highest and lowest log-cortisol levels. Findings indicate that, when examined together, overall cortisol output was not associated with either outcome, but a greater range in cortisol throughout the day was associated with both lower allostatic load and higher cognitive functioning. Results emphasize the importance of dynamic daily processes, assessed either using slopes or dynamic range, to both physiological and cognitive functioning.
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Registered trials
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