ArticleScientific reports2019
The incidence and etiology of sixth cranial nerve palsy in Koreans: A 10-year nationwide cohort study.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Prevalence of non-strabismic binocular vision anomalies and age-related changes in binocular vision among middle-aged and older adults: a systematic review.BMC ophthalmology · 2025Pooled it
- The relationship between glycaemic status and the risk of third, fourth and sixth cranial nerve palsy: a nationwide population-based study (2009-2018).Eye (London, England) · 2026Article
- Healthcare costs due to diplopia in Korea: analyses using the public data of Health Insurance Review and Assessment Service.Frontiers in neurology · 2026Article
- Outcomes of Strabismus Surgery in Patients with Cranial Nerve Palsy.Journal of clinical medicine · 2025Article
- Long term efficacy of recession and resection for abducens nerve palsy with targeting overcorrection of 5 prism diopters.Scientific reports · 2025Article
- Abducens nerve palsy in patients with spontaneous intraventricular hemorrhage: A case report.Medicine · 2025Article
- Ocular motor cranial neuropathy and risk of thyroid cancer: A Korean population-based study.PloS one · 2025Article
- Morphometric analysis of the abducens nerve in the petroclival region.Frontiers in surgery · 2025Article
- Cranial Nerve Palsy and Risk of Kidney Cancer: A Nationwide Population-Based Study.Medicina (Kaunas, Lithuania) · 2024Article
- Torsion and clinical features in patients with acquired fourth cranial nerve palsy.Scientific reports · 2024Article
- Retrospective Analysis of Factors Related to the Long-Term Recovery of Third, Fourth, and Sixth Cranial Nerve Palsy with Etiologies and Clinical Course in a Tertiary Hospital.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Abducens Nerve Palsy in a Patient with COVID-19: A Case Report.Sisli Etfal Hastanesi tip bulteni · 2024Article
- Outcomes and Factors Associated with Successful Strabismus Surgery for Abducens Nerve Palsies: A Retrospective Study and Literature Review.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Ocular motility disorders following coronavirus disease-19 vaccination.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Association between migraine and risk of ocular motor cranial nerve palsy.Scientific reports · 2022Article
- Liver enzymes and risk of ocular motor cranial nerve palsy: a nationwide population-based study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Article
- Clinical profile and management of sixth nerve palsy in pediatric patients (0-15 years) in Southern India - A hospital-based study.Indian journal of ophthalmology · 2022Article
- Isolated Bilateral Abducens Palsy as a Presenting Feature of Multi-Infarct State: A Case Report.Cureus · 2022Article
- The Immediate Onset of Isolated and Unilateral Abducens Nerve Palsy Associated with COVID-19 Infection: A Case Report and Literature Review.Internal medicine (Tokyo, Japan) · 2022Review
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to investigate the incidence, prevalence, and etiology of sixth cranial nerve (CN6) palsy in the general Korean population. The nationally representative dataset of the Korea National Health Insurance Service-National Sample Cohort from 2006 through 2015 was analyzed. The incidence and prevalence of CN6 palsy were estimated in the cohort population, confirming that incident cases of CN6 palsy involved a preceding disease-free period of ≥4 years. The etiologies of CN6 palsy were presumed using comorbidity conditions. Among the 1,108,256 cohort subjects, CN6 palsy developed in 486 patients during the 10-year follow-up. The overall incidence of CN6 palsy was estimated to be 4.66 per 100,000 person-years (95% confidence interval [CI], 4.26-5.08) in the general population. This incidence increased with age, accelerating after 60 years of age and peaking at 70-74 years of age. The mean male-to-female incidence ratio was estimated as 1.41 in the whole population, and the incidence and prevalence of CN6 palsy showed an increasing trend over time in the study period. Surgical incidence for CN6 palsy was only 0.19 per 100,000 person-years (95% CI, 0.12-0.29). The etiologies were presumed to be vascular (56.6%), idiopathic (27.2%), neoplastic (5.6%), and traumatic (4.9%). In conclusion, the incidence of CN6 palsy increases with age, peaking at around 70 years, and shows a mild male predominance in Koreans.
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