Evidence map›Paper›PMID 31804571›Full record

Trial reportScientific reports2019

Associations between echocardiographic findings and prospective changes in residual renal function in patients new to peritoneal dialysis.

Sara Mahdavi, Kibar Yared, George Wu, Billy Omar, Dinesh Savundra, Gordon Nagai, Edgar Hockmann, Anton Svendrovski, Antonio Bellasi, Paul Tam and 1 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sara MahdaviDepartment of Nephrology, The Scarborough Hospital, Toronto, Canada.
Kibar YaredDepartment of Nephrology, The Scarborough Hospital, Toronto, Canada.
George WuFaculty of Medicine, University of Toronto, Toronto, Canada.
Billy OmarDepartment of Nephrology, The Scarborough Hospital, Toronto, Canada.
Dinesh SavundraDepartment of Nephrology, The Scarborough Hospital, Toronto, Canada.
Gordon NagaiDepartment of Nephrology, The Scarborough Hospital, Toronto, Canada.
Edgar HockmannFaculty of Medicine, University of Toronto, Toronto, Canada.
Anton SvendrovskiPrivate Biostatistics Consultant, Toronto, Canada.
Antonio BellasiAziende Socio Sanitarie Territoriale Papa Giovanni XXIII, Bergamo, Italy.ORCID http://orcid.org/0000-0001-7830-1645
Paul TamDepartment of Nephrology, The Scarborough Hospital, Toronto, Canada.
Tabo SikanetaDepartment of Nephrology, The Scarborough Hospital, Toronto, Canada. tabosikaneta@yahoo.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although echocardiograms are often performed when peritoneal dialysis is started, associations between commonly reported findings and prospective changes in renal function remain understudied. Ninety-nine of 101 patients in the Trio Trial had transthoracic echocardiograms within 6 months of dialysis initiation, and measurements of residual renal function every six weeks for up to two years. Generalized mixed modelling linear regression in STATA was used to examine associations between left atrial size, left ventricular hypertrophy, left ventricular ejection fraction, right ventricular systolic pressure, and left valvular calcification with subsequent slopes in renal function. After echocardiography (performed a median of 16 days following peritoneal dialysis initiation) right ventricular systolic pressure was associated with faster, while declining left ventricular ejection fraction and valvular calcification were associated with slower declines in residual renal function. Future studies could be conducted to confirm these findings, and identify pathophysiological mechanisms.

Indexed as

Models, BiologicalPeritoneal DialysisAgedCreatinineDisease ProgressionEchocardiographyFemaleFollow-Up StudiesGlomerular Filtration RateHumansHypertrophy, Left VentricularKidneyKidney Failure, ChronicLinear ModelsMaleMiddle AgedCreatinineUrea

Identifiers

PMID31804571
PMCPMC6895151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.