Evidence map›Paper›PMID 31804179›Full record

ArticleeLife2019

Distinct roles for

Nealia Cm House, Erica J Polleys, Ishtiaque Quasem, Marjorie De la Rosa Mejia, Cailin E Joyce, Oliver Takacsi-Nagy, Jocelyn E Krebs, Stephen M Fuchs, Catherine H Freudenreich

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Histone Phosphorylation in DNA Damage Response.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Review
  5. Identification and characterization of histones inNAR genomics and bioinformatics · 2021
    Article
  6. Homologous recombination within repetitive DNA.Current opinion in genetics & development · 2021
    Review
  7. Article
  8. Structure-forming repeats and their impact on genome stability.Current opinion in genetics & development · 2021
    Review
  9. Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Nealia Cm House *Department of Biology, Tufts University, Medford, United States.
Erica J Polleys *Department of Biology, Tufts University, Medford, United States.
Ishtiaque QuasemDepartment of Biology, Tufts University, Medford, United States.
Marjorie De la Rosa MejiaDepartment of Biology, Tufts University, Medford, United States.
Cailin E JoyceDepartment of Biology, Tufts University, Medford, United States.
Oliver Takacsi-NagyDepartment of Biology, Tufts University, Medford, United States.
Jocelyn E KrebsDepartment of Biological Sciences, University of Alaska Anchorage, Anchorage, United States.
Stephen M FuchsDepartment of Biology, Tufts University, Medford, United States.
Catherine H FreudenreichDepartment of Biology, Tufts University, Medford, United States.ORCID 0000-0002-1652-2917
Tufts University · USBoston University · USUniversity of Alaska Anchorage · US

Funding

Mutations Arising During DNA RepairP01GM105473 · NIGMS · BRANDEIS UNIVERSITY · PI LOVETT, SUSAN THOMAS · 2014 to 2018
$8.6M
American Cancer Society PF-18-125-10-DMCNIGMS NIH HHS P01 GM105473NIH HHS P01GM105473
6 · The paper itself

Abstract

CAG/CTG trinuncleotide repeats are fragile sequences that when expanded form DNA secondary structures and cause human disease. We evaluated CAG/CTG repeat stability and repair outcomes in histone H2 mutants in

Indexed as

Genomic InstabilityRecombination, GeneticRepetitive Sequences, Nucleic AcidHistonesProtein IsoformsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsThreonineHistonesProtein IsoformsSaccharomyces cerevisiae ProteinsThreonineCAG trinucleotide repeatchromosomesDNA recombinationDNA repairgene expressiongeneticsgenomicshistone H2Ahistone phosphorylationS. cerevisiae

Identifiers

PMID31804179
PMCPMC6927750
OpenAlexW2993369168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.