ArticleThe Angle orthodontist2020
Evaluation of toxicity and response to oxidative stress generated by orthodontic bands in human gingival fibroblasts.
Article in The Angle orthodontist, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Cytotoxicity and genotoxicity of orthodontic bands after aging: an in-vitro study.BMC oral health · 2025Article
- Antibacterial and Antioxidant Effects of Magnesium Alloy on Titanium Dental Implants.Computational and mathematical methods in medicine · 2022Article
- Causation of Oxidative Stress and Defense Response of a Yeast Cell Model after Treatment with Orthodontic Alloys Consisting of Metal Ions.Antioxidants (Basel, Switzerland) · 2021Article
- Risk Assessment of Oxidative Stress Induced by Metal Ions Released from Fixed Orthodontic Appliances during Treatment and Indications for Supportive Antioxidant Therapy: A Narrative Review.Antioxidants (Basel, Switzerland) · 2021Review
- Cytotoxic evaluation of two orthodontic silver solder materials on human periodontal ligament fibroblast cells and the effects of antioxidant and antiapoptotic reagents.The Angle orthodontist · 2021Article
- Are Metal Ions That Make up Orthodontic Alloys Cytotoxic, and Do They Induce Oxidative Stress in a Yeast Cell Model?International journal of molecular sciences · 2020Article
- Assessment of cytotoxicity of clear aligners coated with zinc oxide nanoparticles.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the cytotoxicity of stainless-steel orthodontic bands and their influence on the expression of the antioxidant genes in human gingival fibroblasts. MATERIALS AND
methodsTen bands of each brand (Dentsply-Sirona, Dentaurum, TP Orthodontics, and Morelli) were conditioned in 0.2 g/mL culture medium at 37°C for 14 days, and the corresponding conditioned media were applied over the fibroblasts. Cell viability was assessed after 24, 48, and 72 hours of exposure to the conditioned media by trypan blue exclusion assay. Expression of the antioxidant defense genes peroxiredoxin 1 (
resultsAll bands promoted a reduction in the number of viable cells in the periods of 48 and 72 hours (
conclusionsThe orthodontic bands showed toxicity to fibroblasts and increased the expression of
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.